AutismKB 2.0

Annotation Detail for AGAP3


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Basic Information Top
Gene Symbol:AGAP3 ( CENTG3,CRAG,FLJ16146,FLJ34452,MRIP-1 )
Gene Full Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Band: 7q36.1
Quick LinksEntrez ID:116988; OMIM: NA; Uniprot ID:AGAP3_HUMAN; ENSEMBL ID: ENSG00000133612; HGNC ID: 16923
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult159 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor6 / 9417863
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor22 / 26384583
glioma16 / 106883149
head and neck tumor8 / 13630258
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor15 / 103127145
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal206 / 336030761
ovarian tumor9 / 76682117
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder1 / 2975733
blood1 / 1234788
bone6 / 7165583
bone marrow1 / 4880120
brain110 / 110098999
cervix1 / 4817120
connective tissue4 / 14925526
ear2 / 16212123
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye24 / 211054113
heart3 / 8962633
intestine9 / 23447238
kidney9 / 21177742
larynx1 / 2414541
liver4 / 20774319
lung27 / 33697480
lymph0 / 442700 
lymph node0 / 916100 
mammary gland15 / 15327197
mouth2 / 6705229
muscle3 / 10771527
nerve3 / 15768190
ovary11 / 102051107
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate8 / 18934542
salivary gland1 / 2015549
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis16 / 33044248
thymus4 / 8113149
thyroid5 / 47473105
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P317622
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.62 ± 0.59
Basal Forebrain4.65 ± 0.49
Basal Part of Pons5.05 ± 0.67
Cerebellar Cortex5.1 ± 0.65
Cerebellar Nuclei4.03 ± 0.58
Claustrum4.42 ± 1.12
Epithalamus4.62 ± 0.95
Frontal Lobe4.83 ± 0.65
Globus Pallidus4.06 ± 0.53
Hypothalamus4.31 ± 0.85
Insula4.9 ± 0.56
Limbic Lobe4.68 ± 0.76
Mesencephalon4.56 ± 0.7
Myelencephalon4.6 ± 0.74
Occipital Lobe4.04 ± 0.76
Parietal Lobe4.54 ± 0.66
Pontine Tegmentum4.51 ± 0.65
Striatum3.94 ± 0.6
Subthalamus4.85 ± 0.94
Temporal Lobe4.93 ± 0.63
Thalamus4.54 ± 0.65
White Matter4.39 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Centg3CBCerebellum81.62
62.31
Centg3CTXCerebral cortex72.17
51.39
Centg3HIPHippocampal region80.62
82.65
Centg3HPFHippocampal formation83.29
76.11
Centg3HYHypothalamus51.81
29.07
Centg3LSXLateral septal complex53.57
29.82
Centg3MBMidbrain55.25
35.14
Centg3MYMedulla66.02
55.7
Centg3OLFOlfactory bulb78.69
58.87
Centg3PPons58.1
49.71
Centg3PALPallidum44.68
29.9
Centg3RHPRetrohippocampal region79.98
66.77
Centg3sAMYStriatum-like amygdalar nuclei54.36
29.31
Centg3STRStriatum43.93
22.11
Centg3STRdStriatum dorsal region38.71
18.85
Centg3STRvStriatum ventral region50
25.41
Centg3THThalamus70.81
50.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018