AutismKB 2.0

Annotation Detail for IP6K3


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Basic Information Top
Gene Symbol:IP6K3 ( IHPK3,INSP6K3,MGC102928 )
Gene Full Name: inositol hexakisphosphate kinase 3
Band: 6p21.31
Quick LinksEntrez ID:117283; OMIM: 606993; Uniprot ID:IP6K3_HUMAN; ENSEMBL ID: ENSG00000161896; HGNC ID: 17269
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal63 / 336030718
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain17 / 110098915
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart6 / 8962666
intestine0 / 2344720 
kidney3 / 21177714
larynx0 / 241450 
liver6 / 20774328
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth5 / 6705274
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P168130
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.22 ± 1.05
Basal Forebrain2.22 ± 0.47
Basal Part of Pons2.39 ± 0.85
Cerebellar Cortex2.05 ± 0.65
Cerebellar Nuclei3.79 ± 0.67
Claustrum2.46 ± 0.63
Epithalamus2.86 ± 0.88
Frontal Lobe2.56 ± 1.11
Globus Pallidus4.46 ± 0.46
Hypothalamus2.36 ± 1.31
Insula1.69 ± 0.6
Limbic Lobe2.05 ± 0.83
Mesencephalon2.66 ± 1.13
Myelencephalon2.54 ± 0.95
Occipital Lobe2.27 ± 0.83
Parietal Lobe2.29 ± 0.92
Pontine Tegmentum2.61 ± 0.78
Striatum3.07 ± 0.78
Subthalamus2.54 ± 0.28
Temporal Lobe2.05 ± 0.89
Thalamus2.86 ± 0.77
White Matter5.67 ± 0.04
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ihpk3CBCerebellum6.75
8.46
Ihpk3CTXCerebral cortex4.2
3.83
Ihpk3HIPHippocampal region5.38
5.23
Ihpk3HPFHippocampal formation6.2
5.4
Ihpk3HYHypothalamus0.33
0.34
Ihpk3LSXLateral septal complex0.04
0
Ihpk3MBMidbrain2.24
2.28
Ihpk3MYMedulla6.26
8.36
Ihpk3OLFOlfactory bulb5.64
4.46
Ihpk3PPons4.05
5.16
Ihpk3PALPallidum0.61
0.58
Ihpk3RHPRetrohippocampal region7.88
5.85
Ihpk3sAMYStriatum-like amygdalar nuclei0.16
0.19
Ihpk3STRStriatum1.3
1.08
Ihpk3STRdStriatum dorsal region1.44
1.14
Ihpk3STRvStriatum ventral region2.05
1.78
Ihpk3THThalamus0.83
0.72
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018