AutismKB 2.0

Annotation Detail for PARD3B


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Basic Information Top
Gene Symbol:PARD3B ( ALS2CR19,MGC16131,PAR3B,PAR3L,PAR3LC,PAR3beta,Par3Lb )
Gene Full Name: par-3 partitioning defective 3 homolog B (C. elegans)
Band: 2q33.3
Quick LinksEntrez ID:117583; OMIM: NA; Uniprot ID:PAR3L_HUMAN; ENSEMBL ID: ENSG00000116117; HGNC ID: 14446
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor8 / 26384530
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal77 / 336030722
ovarian tumor5 / 7668265
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye7 / 21105433
heart4 / 8962644
intestine5 / 23447221
kidney6 / 21177728
larynx1 / 2414541
liver3 / 20774314
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle4 / 10771537
nerve0 / 157680 
ovary5 / 10205148
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P113367
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.23 ± 0.56
Basal Forebrain5.49 ± 0.22
Basal Part of Pons4.19 ± 0.71
Cerebellar Cortex4.07 ± 0.42
Cerebellar Nuclei5.04 ± 0.56
Claustrum4.47 ± 0.72
Epithalamus6.4 ± 0.62
Frontal Lobe4.53 ± 0.69
Globus Pallidus6.24 ± 0.39
Hypothalamus4.87 ± 0.9
Insula4.25 ± 0.68
Limbic Lobe4.47 ± 0.79
Mesencephalon4.86 ± 0.61
Myelencephalon4.82 ± 0.73
Occipital Lobe4.83 ± 0.67
Parietal Lobe4.58 ± 0.7
Pontine Tegmentum4.68 ± 0.83
Striatum5.77 ± 0.47
Subthalamus3.9 ± 0.6
Temporal Lobe4.38 ± 0.68
Thalamus4.71 ± 0.56
White Matter6.38 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Als2cr19CBCerebellum1.26
1.93
Als2cr19CTXCerebral cortex2.39
1.87
Als2cr19HIPHippocampal region1.65
1.72
Als2cr19HPFHippocampal formation4.56
4.53
Als2cr19HYHypothalamus2.43
1.85
Als2cr19LSXLateral septal complex0.18
0.19
Als2cr19MBMidbrain0.5
0.62
Als2cr19MYMedulla0.35
0.38
Als2cr19OLFOlfactory bulb3.25
2.9
Als2cr19PPons0.45
0.55
Als2cr19PALPallidum6.71
5.73
Als2cr19RHPRetrohippocampal region9.15
8.16
Als2cr19sAMYStriatum-like amygdalar nuclei9.06
6.06
Als2cr19STRStriatum3.77
3.41
Als2cr19STRdStriatum dorsal region4.45
4.48
Als2cr19STRvStriatum ventral region1.33
1.02
Als2cr19THThalamus6.88
7.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018