AutismKB 2.0

Annotation Detail for ANTXR2


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Basic Information Top
Gene Symbol:ANTXR2 ( CMG-2,CMG2,FLJ31074,ISH,JHF,MGC111533,MGC45856 )
Gene Full Name: anthrax toxin receptor 2
Band: 4q21.21
Quick LinksEntrez ID:118429; OMIM: 608041; Uniprot ID:ANTR2_HUMAN; ENSEMBL ID: ENSG00000163297; HGNC ID: 21732
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus43 / 56401276
neonate3 / 3109796
infant2 / 2362084
juvenile3 / 5555653
adult101 / 193912152
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor15 / 26384556
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal211 / 336030762
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood12 / 12347897
bone3 / 7165541
bone marrow5 / 48801102
brain28 / 110098925
cervix0 / 481710 
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye9 / 21105442
heart4 / 8962644
intestine13 / 23447255
kidney16 / 21177775
larynx1 / 2414541
liver9 / 20774343
lung11 / 33697432
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth3 / 6705244
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta29 / 280825103
prostate22 / 189345116
salivary gland0 / 201550 
skin9 / 21057442
spleen3 / 5395255
stomach1 / 9661910
testis9 / 33044227
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord2 / 13680146
uterus38 / 232878163
vascular9 / 51780173
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P170733
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.21 ± 0.29
Basal Forebrain6.23 ± 0.41
Basal Part of Pons5.31 ± 0.2
Cerebellar Cortex5.71 ± 0.24
Cerebellar Nuclei6.45 ± 0.44
Claustrum6.41 ± 0.5
Epithalamus7.7 ± 0.71
Frontal Lobe6.05 ± 0.44
Globus Pallidus7.56 ± 0.43
Hypothalamus6.36 ± 0.62
Insula6.21 ± 0.56
Limbic Lobe5.89 ± 0.56
Mesencephalon6.35 ± 0.52
Myelencephalon6.3 ± 0.58
Occipital Lobe6.78 ± 0.73
Parietal Lobe6.3 ± 0.45
Pontine Tegmentum6.34 ± 0.37
Striatum6.71 ± 0.48
Subthalamus6.23 ± 0.32
Temporal Lobe5.91 ± 0.48
Thalamus6.26 ± 0.39
White Matter5.95 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Antxr2CBCerebellum1.1
1.48
Antxr2CTXCerebral cortex2.67
2.07
Antxr2HIPHippocampal region1.59
1.47
Antxr2HPFHippocampal formation1.65
1.36
Antxr2HYHypothalamus0.39
0.28
Antxr2LSXLateral septal complex0.07
0.05
Antxr2MBMidbrain1.1
1.45
Antxr2MYMedulla1.49
1.52
Antxr2OLFOlfactory bulb2.79
2.77
Antxr2PPons3.49
4.61
Antxr2PALPallidum1.76
1.32
Antxr2RHPRetrohippocampal region1.75
1.17
Antxr2sAMYStriatum-like amygdalar nuclei4.7
3.32
Antxr2STRStriatum0.63
0.45
Antxr2STRdStriatum dorsal region0.39
0.31
Antxr2STRvStriatum ventral region0.38
0.23
Antxr2THThalamus0.52
0.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANTR2_HUMAN_385 7 385 391 GVGGIKR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018