AutismKB 2.0

Annotation Detail for C11orf74


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Basic Information Top
Gene Symbol:C11orf74 ( FLJ38678 )
Gene Full Name: chromosome 11 open reading frame 74
Band: 11p12
Quick LinksEntrez ID:119710; OMIM: NA; Uniprot ID:CK074_HUMAN; ENSEMBL ID: ENSG00000166352; HGNC ID: 25142
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal48 / 336030714
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow1 / 4880120
brain8 / 11009897
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye6 / 21105428
heart5 / 8962655
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus2 / 2328788
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6130_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.13 ± 0.41
Basal Forebrain6.26 ± 0.23
Basal Part of Pons6.69 ± 0.3
Cerebellar Cortex6.16 ± 0.25
Cerebellar Nuclei6.59 ± 0.28
Claustrum6.73 ± 0.38
Epithalamus6.94 ± 0.29
Frontal Lobe6.5 ± 0.27
Globus Pallidus6.52 ± 0.44
Hypothalamus6.49 ± 0.31
Insula6.52 ± 0.19
Limbic Lobe6.12 ± 0.4
Mesencephalon6.36 ± 0.42
Myelencephalon6.3 ± 0.38
Occipital Lobe5.83 ± 0.48
Parietal Lobe6.33 ± 0.28
Pontine Tegmentum6.23 ± 0.26
Striatum5.81 ± 0.41
Subthalamus6.3 ± 0.24
Temporal Lobe6.42 ± 0.31
Thalamus6.19 ± 0.32
White Matter6.54 ± 0.23
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
B230118H07RikCBCerebellum6.3
6.75
B230118H07RikCTXCerebral cortex0.56
0.5
B230118H07RikHIPHippocampal region2.04
2.07
B230118H07RikHPFHippocampal formation1.63
1.51
B230118H07RikHYHypothalamus0.27
0.28
B230118H07RikLSXLateral septal complex0.03
0
B230118H07RikMBMidbrain0.76
0.83
B230118H07RikMYMedulla1.75
1.92
B230118H07RikOLFOlfactory bulb0.43
0.31
B230118H07RikPPons0.62
0.81
B230118H07RikPALPallidum1.12
1.07
B230118H07RikRHPRetrohippocampal region0.84
0.6
B230118H07RiksAMYStriatum-like amygdalar nuclei0.17
0.22
B230118H07RikSTRStriatum0.18
0.3
B230118H07RikSTRdStriatum dorsal region0.27
0.48
B230118H07RikSTRvStriatum ventral region0.03
0.04
B230118H07RikTHThalamus0.95
0.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018