Annotation Detail for CLTB
Basic Information Top
| Gene Symbol: | CLTB ( LCB ) |
|---|---|
| Gene Full Name: | clathrin, light chain B |
| Band: | 5q35.2 |
| Quick Links | Entrez ID:1212; OMIM: 118970; Uniprot ID:CLCB_HUMAN; ENSEMBL ID: ENSG00000175416; HGNC ID: 2091 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.484241
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 1 / 62319 | 16 |  |
| fetus | 9 / 564012 | 15 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 97 / 1939121 | 50 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 16 / 94178 | 169 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 2 / 263845 | 7 |  |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 8 / 136302 | 58 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 4 / 95842 | 41 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 105 / 3360307 | 31 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 36 / 1100989 | 32 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 15 / 211054 | 71 | |
| heart | 2 / 89626 | 22 | |
| intestine | 14 / 234472 | 59 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 1 / 24145 | 41 | |
| liver | 2 / 207743 | 9 | |
| lung | 6 / 336974 | 17 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 17 / 153271 | 110 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 7 / 107715 | 64 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 5 / 41328 | 120 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 15 / 280825 | 53 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 8 / 210574 | 37 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 6 / 96619 | 62 | |
| testis | 1 / 330442 | 3 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 216934_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 5.4 | |
| Adipocyte | 4.6 | |
| AdrenalCortex | 5.15 | |
| Adrenalgland | 3.85 | |
| Amygdala | 4.65 | |
| Appendix | 4.7 | |
| AtrioventricularNode | 4.1 | |
| BDCA4+_DentriticCells | 4.9 | |
| Bonemarrow | 4.6 | |
| BronchialEpithelialCells | 4.3 | |
| CD105+_Endothelial | 4.6 | |
| CD14+_Monocytes | 4.7 | |
| CD19+_BCells(neg._sel.) | 4.7 | |
| CD33+_Myeloid | 5.6 | |
| CD34+ | 5.55 | |
| CD4+_Tcells | 4.75 | |
| CD56+_NKCells | 5.25 | |
| CD71+_EarlyErythroid | 4.15 | |
| CD8+_Tcells | 4.2 | |
| CardiacMyocytes | 6.1 | |
| Caudatenucleus | 4 | |
| Cerebellum | 3.65 | |
| CerebellumPeduncles | 5.3 | |
| CiliaryGanglion | 3.15 | |
| CingulateCortex | 4.65 | |
| Colorectaladenocarcinoma | 4.5 | |
| DorsalRootGanglion | 3.6 | |
| FetalThyroid | 4.4 | |
| Fetalbrain | 4.4 | |
| Fetalliver | 3.9 | |
| Fetallung | 3.65 | |
| GlobusPallidus | 3.35 | |
| Heart | 6.85 | |
| Hypothalamus | 5.1 | |
| Kidney | 3.8 | |
| Leukemia_chronicMyelogenousK-562 | 5 | |
| Leukemia_promyelocytic-HL-60 | 4 | |
| Leukemialymphoblastic(MOLT-4) | 3.55 | |
| Liver | 6.35 | |
| Lung | 4.9 | |
| Lymphnode | 3.75 | |
| Lymphoma_burkitts(Daudi) | 6 | |
| Lymphoma_burkitts(Raji) | 6.55 | |
| MedullaOblongata | 4.1 | |
| OccipitalLobe | 3.95 | |
| OlfactoryBulb | 3.5 | |
| Ovary | 3 | |
| Pancreas | 3.65 | |
| PancreaticIslet | 4.8 | |
| ParietalLobe | 4.85 | |
| Pituitary | 5.2 | |
| Placenta | 4.5 | |
| Pons | 4.3 | |
| PrefrontalCortex | 5.7 | |
| Prostate | 7.2 | |
| Salivarygland | 3.6 | |
| SkeletalMuscle | 6.1 | |
| Skin | 3.55 | |
| SmoothMuscle | 5 | |
| Spinalcord | 5 | |
| SubthalamicNucleus | 4.15 | |
| SuperiorCervicalGanglion | 5.8 | |
| TemporalLobe | 4.65 | |
| Testis | 3.8 | |
| TestisGermCell | 3.65 | |
| TestisIntersitial | 3.8 | |
| TestisLeydigCell | 4.4 | |
| TestisSeminiferousTubule | 4.25 | |
| Thalamus | 4.65 | |
| Thymus | 3.45 | |
| Thyroid | 5.55 | |
| Tongue | 4.6 | |
| Tonsil | 4.5 | |
| Trachea | 3.85 | |
| TrigeminalGanglion | 4.8 | |
| Uterus | 3.65 | |
| UterusCorpus | 4.2 | |
| WholeBlood | 4.85 | |
| Wholebrain | 3.75 | |
| colon | 4.55 | |
| pineal_day | 5.54 | |
| pineal_night | 5.44 | |
| retina | 6.075 | |
| small_intestine | 4.95 | |
- Probe name: CUST_9320_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 10.59 ± 0.46 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 10.21 ± 0.34 | |
| Basal Part of Pons | 10.43 ± 0.25 | |
| Cerebellar Cortex | 9.97 ± 0.29 | |
| Cerebellar Nuclei | 10.24 ± 0.32 | |
| Claustrum | 10.76 ± 0.61 | |
| Epithalamus | 9.17 ± 0.39 | |
| Frontal Lobe | 10.07 ± 0.46 | |
| Globus Pallidus | 10.19 ± 0.2 | |
| Hypothalamus | 9.82 ± 0.35 | |
| Insula | 10.06 ± 0.6 | |
| Limbic Lobe | 10.42 ± 0.53 | |
| Mesencephalon | 10.19 ± 0.49 | |
| Myelencephalon | 10.21 ± 0.47 | |
| Occipital Lobe | 10.44 ± 0.5 | |
| Parietal Lobe | 10.27 ± 0.49 | |
| Pontine Tegmentum | 10.06 ± 0.45 | |
| Striatum | 10.37 ± 0.56 | |
| Subthalamus | 10.11 ± 0.17 | |
| Temporal Lobe | 10.2 ± 0.43 | |
| Thalamus | 10.21 ± 0.41 | |
| White Matter | 9.33 ± 0.36 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cltb | CB | Cerebellum | 10.98 | |
| 12.72 | | |||
| Cltb | CTX | Cerebral cortex | 30.55 | |
| 22.33 | | |||
| Cltb | HIP | Hippocampal region | 16.23 | |
| 15.19 | | |||
| Cltb | HPF | Hippocampal formation | 21.35 | |
| 18.06 | | |||
| Cltb | HY | Hypothalamus | 7.66 | |
| 6.4 | | |||
| Cltb | LSX | Lateral septal complex | 3.02 | |
| 2.64 | | |||
| Cltb | MB | Midbrain | 13.11 | |
| 14 | | |||
| Cltb | MY | Medulla | 34.1 | |
| 43.22 | | |||
| Cltb | OLF | Olfactory bulb | 29.47 | |
| 25.2 | | |||
| Cltb | P | Pons | 21.21 | |
| 26.52 | | |||
| Cltb | PAL | Pallidum | 18.76 | |
| 20.08 | | |||
| Cltb | RHP | Retrohippocampal region | 31.84 | |
| 23.4 | | |||
| Cltb | sAMY | Striatum-like amygdalar nuclei | 10.17 | |
| 7.54 | | |||
| Cltb | STR | Striatum | 11.33 | |
| 8.63 | | |||
| Cltb | STRd | Striatum dorsal region | 11.82 | |
| 9.07 | | |||
| Cltb | STRv | Striatum ventral region | 14.02 | |
| 10.16 | | |||
| Cltb | TH | Thalamus | 20.08 | |
| 17.39 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CLCB_HUMAN_0 | 0 | 0 | 0 | VAQLCDFNPK | PRIDE |
| CLCB_HUMAN_143 | 13 | 143 | 155 | QSEQVEKNKINNR | PRIDE |
| CLCB_HUMAN_194 | 10 | 194 | 203 | VAQLCDFNPK | PRIDE |
| PAp00004739 | 7 | 198 | 204 | LCDFNPK | Peptide Atlas |