AutismKB 2.0

Annotation Detail for IKBIP


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Basic Information Top
Gene Symbol:IKBIP ( FLJ31051,IKIP )
Gene Full Name: IKBKB interacting protein
Band: 12q23.1
Quick LinksEntrez ID:121457; OMIM: 609861; Uniprot ID:IKIP_HUMAN; ENSEMBL ID: ENSG00000166130; HGNC ID: 26430
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst4 / 6231964
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal81 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone5 / 7165569
bone marrow1 / 4880120
brain8 / 11009897
cervix1 / 4817120
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine6 / 23447225
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung11 / 33697432
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis4 / 33044212
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P303210
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.85 ± 1.01
Basal Forebrain2.3 ± 0.21
Basal Part of Pons2.04 ± 0.38
Cerebellar Cortex2.12 ± 0.58
Cerebellar Nuclei2.65 ± 0.7
Claustrum3.1 ± 0.76
Epithalamus2.11 ± 0.89
Frontal Lobe2.27 ± 0.66
Globus Pallidus2.72 ± 0.31
Hypothalamus2.44 ± 0.62
Insula2.17 ± 0.48
Limbic Lobe2.34 ± 0.61
Mesencephalon2.53 ± 0.68
Myelencephalon2.42 ± 0.63
Occipital Lobe2.45 ± 0.55
Parietal Lobe2.25 ± 0.65
Pontine Tegmentum2.39 ± 0.63
Striatum2.76 ± 0.61
Subthalamus2.55 ± 0.62
Temporal Lobe2.36 ± 0.67
Thalamus2.34 ± 0.58
White Matter2.71 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1200009F10RikCBCerebellum17.67
19.89
1200009F10RikCTXCerebral cortex14.15
9.16
1200009F10RikHIPHippocampal region15.5
17.73
1200009F10RikHPFHippocampal formation13.87
13.95
1200009F10RikHYHypothalamus12.67
9.89
1200009F10RikLSXLateral septal complex14.1
9.51
1200009F10RikMBMidbrain17.25
15.44
1200009F10RikMYMedulla19.32
20.06
1200009F10RikOLFOlfactory bulb23.76
17.96
1200009F10RikPPons21.49
21.87
1200009F10RikPALPallidum11.71
9.46
1200009F10RikRHPRetrohippocampal region10.8
8.31
1200009F10RiksAMYStriatum-like amygdalar nuclei9.82
6.96
1200009F10RikSTRStriatum8.86
6.55
1200009F10RikSTRdStriatum dorsal region6.07
4.89
1200009F10RikSTRvStriatum ventral region16.19
10.78
1200009F10RikTHThalamus18.9
15.17
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00133582 15 271 285 THLPTIESAIHSVLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018