Annotation Detail for FGD4
Basic Information Top
| Gene Symbol: | FGD4 ( CMT4H,DKFZp313E1818,DKFZp434K1572,FLJ34370,FLJ42663,FRABP,MGC57222,ZFYVE6 ) |
|---|---|
| Gene Full Name: | FYVE, RhoGEF and PH domain containing 4 |
| Band: | 12p11.21 |
| Quick Links | Entrez ID:121512; OMIM: 611104; Uniprot ID:FGD4_HUMAN; ENSEMBL ID: ENSG00000139132; HGNC ID: 19125 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.117835
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 4 / 62319 | 64 |  |
| fetus | 28 / 564012 | 49 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 49 / 1939121 | 25 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 7 / 119369 | 58 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 117 / 3360307 | 34 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 6 / 123478 | 48 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 35 / 1100989 | 31 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 7 / 211054 | 33 | |
| heart | 2 / 89626 | 22 | |
| intestine | 7 / 234472 | 29 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 4 / 207743 | 19 | |
| lung | 1 / 336974 | 2 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 12 / 214812 | 55 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 2 / 210574 | 9 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 5 / 96619 | 51 | |
| testis | 36 / 330442 | 108 | |
| thymus | 1 / 81131 | 12 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 2 / 51780 | 38 | |
Microarray in - Probe name: A_24_P914639
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.44 ± 1 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 2.04 ± 0.25 | |
| Basal Part of Pons | 1.67 ± 0.29 | |
| Cerebellar Cortex | 1.9 ± 0.86 | |
| Cerebellar Nuclei | 2.3 ± 0.84 | |
| Claustrum | 2.92 ± 0.87 | |
| Epithalamus | 1.7 ± 0.74 | |
| Frontal Lobe | 1.91 ± 0.71 | |
| Globus Pallidus | 2.64 ± 0.41 | |
| Hypothalamus | 2.12 ± 0.7 | |
| Insula | 1.85 ± 0.53 | |
| Limbic Lobe | 2.07 ± 0.71 | |
| Mesencephalon | 2.24 ± 0.81 | |
| Myelencephalon | 2.07 ± 0.76 | |
| Occipital Lobe | 2.07 ± 0.78 | |
| Parietal Lobe | 2.07 ± 0.84 | |
| Pontine Tegmentum | 2.09 ± 0.75 | |
| Striatum | 2.21 ± 0.61 | |
| Subthalamus | 2.18 ± 0.55 | |
| Temporal Lobe | 1.93 ± 0.72 | |
| Thalamus | 2.07 ± 0.81 | |
| White Matter | 2.62 ± 0.21 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Fgd4 | CB | Cerebellum | 4.4 | |
| 5.98 | | |||
| Fgd4 | CTX | Cerebral cortex | 3.17 | |
| 2.93 | | |||
| Fgd4 | HIP | Hippocampal region | 10.28 | |
| 9.7 | | |||
| Fgd4 | HPF | Hippocampal formation | 8.78 | |
| 7.46 | | |||
| Fgd4 | HY | Hypothalamus | 0.72 | |
| 0.91 | | |||
| Fgd4 | LSX | Lateral septal complex | 0.3 | |
| 0.2 | | |||
| Fgd4 | MB | Midbrain | 2.08 | |
| 2.43 | | |||
| Fgd4 | MY | Medulla | 6.29 | |
| 6.41 | | |||
| Fgd4 | OLF | Olfactory bulb | 8.7 | |
| 6.24 | | |||
| Fgd4 | P | Pons | 2.68 | |
| 2.92 | | |||
| Fgd4 | PAL | Pallidum | 1.02 | |
| 0.76 | | |||
| Fgd4 | RHP | Retrohippocampal region | 6.49 | |
| 4.52 | | |||
| Fgd4 | sAMY | Striatum-like amygdalar nuclei | 1.87 | |
| 1.42 | | |||
| Fgd4 | STR | Striatum | 1.4 | |
| 1.43 | | |||
| Fgd4 | STRd | Striatum dorsal region | 1.5 | |
| 1.88 | | |||
| Fgd4 | STRv | Striatum ventral region | 1.37 | |
| 0.74 | | |||
| Fgd4 | TH | Thalamus | 2.76 | |
| 2.78 | |