AutismKB 2.0

Annotation Detail for PLD4


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Basic Information Top
Gene Symbol:PLD4 ( C14orf175 )
Gene Full Name: phospholipase D family, member 4
Band: 14q32.33
Quick LinksEntrez ID:122618; OMIM: NA; Uniprot ID:PLD4_HUMAN; ENSEMBL ID: ENSG00000166428; HGNC ID: 23792
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma3 / 7175541
non-neoplasia2 / 9725020
normal48 / 336030714
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood5 / 12347840
bone0 / 716550 
bone marrow9 / 48801184
brain19 / 110098917
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph3 / 4427067
lymph node5 / 9161054
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen8 / 53952148
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord1 / 1368073
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P88228
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.91 ± 1.01
Basal Forebrain2.23 ± 0.28
Basal Part of Pons2.78 ± 0.91
Cerebellar Cortex2.26 ± 0.79
Cerebellar Nuclei3.09 ± 0.57
Claustrum3.27 ± 0.94
Epithalamus2.67 ± 0.82
Frontal Lobe2.36 ± 0.79
Globus Pallidus3.43 ± 0.68
Hypothalamus2.24 ± 0.96
Insula2.36 ± 0.47
Limbic Lobe2.63 ± 0.82
Mesencephalon2.46 ± 0.8
Myelencephalon2.52 ± 0.74
Occipital Lobe2.49 ± 0.99
Parietal Lobe2.48 ± 0.9
Pontine Tegmentum2.42 ± 0.8
Striatum2.87 ± 0.73
Subthalamus2.48 ± 0.81
Temporal Lobe2.42 ± 0.8
Thalamus2.38 ± 0.7
White Matter3.28 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pld4CBCerebellum3.29
3.58
Pld4CTXCerebral cortex15.53
6.7
Pld4HIPHippocampal region7.12
4.19
Pld4HPFHippocampal formation8.23
4.17
Pld4HYHypothalamus3.03
1.07
Pld4LSXLateral septal complex3.29
1.27
Pld4MBMidbrain3.87
1.88
Pld4MYMedulla4.7
2.27
Pld4OLFOlfactory bulb14.36
6.2
Pld4PPons5.09
3.02
Pld4PALPallidum7.38
2.59
Pld4RHPRetrohippocampal region10.11
4.22
Pld4sAMYStriatum-like amygdalar nuclei7.85
3.72
Pld4STRStriatum7.72
3.35
Pld4STRdStriatum dorsal region7.46
3.25
Pld4STRvStriatum ventral region9.92
3.99
Pld4THThalamus2.76
1.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00010804 18 375 392 LLVGCGLNTDPTMFPYLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018