Annotation Detail for LEO1
Basic Information Top
| Gene Symbol: | LEO1 ( RDL ) |
|---|---|
| Gene Full Name: | Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) |
| Band: | 15q21.2 |
| Quick Links | Entrez ID:123169; OMIM: 610507; Uniprot ID:LEO1_HUMAN; ENSEMBL ID: ENSG00000166477; HGNC ID: 30401 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.567662
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 13 / 564012 | 23 | |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 3 / 55556 | 53 |  |
| adult | 67 / 1939121 | 34 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 2 / 17290 | 115 | |
| gastrointestinal tumor | 8 / 119369 | 67 | |
| germ cell tumor | 1 / 263845 | 3 |  |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 11 / 95842 | 114 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 2 / 103127 | 19 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 85 / 3360307 | 25 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 4 / 102680 | 38 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 12 / 125191 | 95 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 1 / 29757 | 33 | |
| blood | 11 / 123478 | 89 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 28 / 1100989 | 25 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 11 / 149255 | 73 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 9 / 215722 | 41 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 6 / 211054 | 28 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 6 / 211777 | 28 | |
| larynx | 1 / 24145 | 41 | |
| liver | 3 / 207743 | 14 | |
| lung | 3 / 336974 | 8 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 6 / 41328 | 145 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 5 / 189345 | 26 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 2 / 210574 | 9 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 6 / 96619 | 62 | |
| testis | 2 / 330442 | 6 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 9 / 232878 | 38 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_4910_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 8.82 ± 0.28 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 8.82 ± 0.09 | |
| Basal Part of Pons | 9.02 ± 0.18 | |
| Cerebellar Cortex | 9.12 ± 0.16 | |
| Cerebellar Nuclei | 8.88 ± 0.31 | |
| Claustrum | 8.85 ± 0.26 | |
| Epithalamus | 8.58 ± 0.36 | |
| Frontal Lobe | 8.82 ± 0.24 | |
| Globus Pallidus | 8.67 ± 0.14 | |
| Hypothalamus | 8.73 ± 0.32 | |
| Insula | 8.86 ± 0.26 | |
| Limbic Lobe | 8.8 ± 0.22 | |
| Mesencephalon | 8.81 ± 0.25 | |
| Myelencephalon | 8.79 ± 0.24 | |
| Occipital Lobe | 9.04 ± 0.2 | |
| Parietal Lobe | 8.92 ± 0.19 | |
| Pontine Tegmentum | 8.84 ± 0.16 | |
| Striatum | 8.79 ± 0.21 | |
| Subthalamus | 8.88 ± 0.02 | |
| Temporal Lobe | 8.85 ± 0.22 | |
| Thalamus | 8.87 ± 0.22 | |
| White Matter | 8.73 ± 0.14 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Leo1 | CB | Cerebellum | 0.78 | |
| 1.3 | | |||
| Leo1 | CTX | Cerebral cortex | 0.36 | |
| 0.72 | | |||
| Leo1 | HIP | Hippocampal region | 0.19 | |
| 0.51 | | |||
| Leo1 | HPF | Hippocampal formation | 0.16 | |
| 0.4 | | |||
| Leo1 | HY | Hypothalamus | 0.06 | |
| 0.08 | | |||
| Leo1 | LSX | Lateral septal complex | 0.31 | |
| 1.47 | | |||
| Leo1 | MB | Midbrain | 0.11 | |
| 0.3 | | |||
| Leo1 | MY | Medulla | 0.19 | |
| 0.34 | | |||
| Leo1 | OLF | Olfactory bulb | 0.87 | |
| 1.72 | | |||
| Leo1 | P | Pons | 0.21 | |
| 0.8 | | |||
| Leo1 | PAL | Pallidum | 0.05 | |
| 0.17 | | |||
| Leo1 | RHP | Retrohippocampal region | 0.12 | |
| 0.23 | | |||
| Leo1 | sAMY | Striatum-like amygdalar nuclei | 0 | |
| 0 | | |||
| Leo1 | STR | Striatum | 0.09 | |
| 0.22 | | |||
| Leo1 | STRd | Striatum dorsal region | 0.05 | |
| 0.08 | | |||
| Leo1 | STRv | Striatum ventral region | 0.08 | |
| 0.05 | | |||
| Leo1 | TH | Thalamus | 0.22 | |
| 0.24 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| LEO1_HUMAN_2 | 17 | 2 | 18 | ADMEDLFGSDADSEAER | PRIDE |
| PAp00063887 | 13 | 462 | 474 | APLQGDHNHLFIR | Peptide Atlas |