AutismKB 2.0

Annotation Detail for CCR7


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Basic Information Top
Gene Symbol:CCR7 ( BLR2,CD197,CDw197,CMKBR7,EBI1 )
Gene Full Name: chemokine (C-C motif) receptor 7
Band: 17q21.2
Quick LinksEntrez ID:1236; OMIM: 600242; Uniprot ID:CCR7_HUMAN; ENSEMBL ID: ENSG00000126353; HGNC ID: 1608
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal124 / 336030736
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood50 / 123478404
bone0 / 716550 
bone marrow1 / 4880120
brain1 / 11009890 
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine4 / 23447217
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx44 / 413281064
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen10 / 53952185
stomach2 / 9661920
testis2 / 3304426
thymus11 / 81131135
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206337_at
Cell line Expression level Expression bar
721_B_lymphoblasts2005.55
Adipocyte5.5
AdrenalCortex5.65
Adrenalgland4.6
Amygdala5.3
Appendix5.7
AtrioventricularNode4.45
BDCA4+_DentriticCells35.2
Bonemarrow13.6
BronchialEpithelialCells5.45
CD105+_Endothelial5.4
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)627.9
CD33+_Myeloid6.8
CD34+7
CD4+_Tcells1359.85
CD56+_NKCells10.45
CD71+_EarlyErythroid5.15
CD8+_Tcells1219.95
CardiacMyocytes7.65
Caudatenucleus4.95
Cerebellum4.5
CerebellumPeduncles6.35
CiliaryGanglion5.75
CingulateCortex5.6
Colorectaladenocarcinoma5.55
DorsalRootGanglion4.65
FetalThyroid5.4
Fetalbrain5.5
Fetalliver4.9
Fetallung4.6
GlobusPallidus4.05
Heart9
Hypothalamus5.75
Kidney4.8
Leukemia_chronicMyelogenousK-5625
Leukemia_promyelocytic-HL-6027.45
Leukemialymphoblastic(MOLT-4)4.45
Liver7.35
Lung6.05
Lymphnode44.75
Lymphoma_burkitts(Daudi)7.25
Lymphoma_burkitts(Raji)293.3
MedullaOblongata4.85
OccipitalLobe4.85
OlfactoryBulb4.25
Ovary3.7
Pancreas4.45
PancreaticIslet5.95
ParietalLobe5.8
Pituitary6.35
Placenta5.75
Pons5.25
PrefrontalCortex6.9
Prostate8.65
Salivarygland12.1
SkeletalMuscle7.4
Skin4.6
SmoothMuscle6.3
Spinalcord5.85
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.95
TemporalLobe5
Testis4.8
TestisGermCell4.6
TestisIntersitial4.8
TestisLeydigCell5.45
TestisSeminiferousTubule4.7
Thalamus5.55
Thymus133.15
Thyroid7.05
Tongue5.4
Tonsil33.6
Trachea4.55
TrigeminalGanglion5.55
Uterus4.55
UterusCorpus4.9
WholeBlood60.3
Wholebrain4.65
colon5.6
pineal_day6.7
pineal_night6.44
retina6.65
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13329_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.52 ± 0.53
Basal Forebrain4.81 ± 0.49
Basal Part of Pons4.21 ± 0.48
Cerebellar Cortex4.92 ± 0.48
Cerebellar Nuclei4.3 ± 0.71
Claustrum4.96 ± 0.92
Epithalamus4.49 ± 0.4
Frontal Lobe4.42 ± 0.59
Globus Pallidus4.83 ± 0.82
Hypothalamus4.43 ± 0.75
Insula4.4 ± 0.35
Limbic Lobe4.51 ± 0.65
Mesencephalon4.58 ± 0.58
Myelencephalon4.55 ± 0.65
Occipital Lobe4.59 ± 0.66
Parietal Lobe4.42 ± 0.65
Pontine Tegmentum4.58 ± 0.59
Striatum4.66 ± 0.54
Subthalamus4.41 ± 0.6
Temporal Lobe4.38 ± 0.65
Thalamus4.47 ± 0.56
White Matter4.91 ± 0.65
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccr7CBCerebellum5.94
8.46
Ccr7CTXCerebral cortex6.39
5.51
Ccr7HIPHippocampal region2.45
2.26
Ccr7HPFHippocampal formation3.51
3.24
Ccr7HYHypothalamus1.24
1.14
Ccr7LSXLateral septal complex0.09
0.06
Ccr7MBMidbrain3.36
3.41
Ccr7MYMedulla7.86
8.02
Ccr7OLFOlfactory bulb13.2
11.14
Ccr7PPons8.28
10.8
Ccr7PALPallidum0.8
0.82
Ccr7RHPRetrohippocampal region5.82
5
Ccr7sAMYStriatum-like amygdalar nuclei0.88
1.11
Ccr7STRStriatum1.74
1.42
Ccr7STRdStriatum dorsal region1.85
1.61
Ccr7STRvStriatum ventral region2.15
1.43
Ccr7THThalamus3.22
2.8
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018