AutismKB 2.0

Annotation Detail for DCUN1D3


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Basic Information Top
Gene Symbol:DCUN1D3 ( 44M2.4,DKFZp686O0290,FLJ41725,MGC48972 )
Gene Full Name: DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
Band: 16p12.3
Quick LinksEntrez ID:123879; OMIM: NA; Uniprot ID:DCNL3_HUMAN; ENSEMBL ID: ENSG00000188215; HGNC ID: 28734
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal22 / 33603076
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine1 / 2344724
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus3 / 23287812
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10018_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.57
Basal Forebrain4.2 ± 0.59
Basal Part of Pons3.82 ± 0.38
Cerebellar Cortex4.62 ± 0.33
Cerebellar Nuclei3.85 ± 0.59
Claustrum4.09 ± 0.78
Epithalamus4.21 ± 0.46
Frontal Lobe4.2 ± 0.59
Globus Pallidus4 ± 0.71
Hypothalamus4.71 ± 0.42
Insula4.12 ± 0.52
Limbic Lobe4.16 ± 0.52
Mesencephalon4.3 ± 0.7
Myelencephalon4.22 ± 0.55
Occipital Lobe4.2 ± 0.5
Parietal Lobe4.38 ± 0.52
Pontine Tegmentum4.24 ± 0.54
Striatum4.01 ± 0.63
Subthalamus4.12 ± 0.5
Temporal Lobe4.2 ± 0.45
Thalamus4.18 ± 0.56
White Matter4.74 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dcun1d3CBCerebellum8.75
9.53
Dcun1d3CTXCerebral cortex12.75
8.97
Dcun1d3HIPHippocampal region10.5
10.64
Dcun1d3HPFHippocampal formation10.29
9.13
Dcun1d3HYHypothalamus1.62
1.17
Dcun1d3LSXLateral septal complex1.15
0.67
Dcun1d3MBMidbrain2.33
2.23
Dcun1d3MYMedulla10.1
10.45
Dcun1d3OLFOlfactory bulb22.81
16.64
Dcun1d3PPons4.93
5.28
Dcun1d3PALPallidum6.88
5.63
Dcun1d3RHPRetrohippocampal region9.92
7.27
Dcun1d3sAMYStriatum-like amygdalar nuclei8.28
6.2
Dcun1d3STRStriatum7.22
5.31
Dcun1d3STRdStriatum dorsal region5.29
4.04
Dcun1d3STRvStriatum ventral region15.45
10.23
Dcun1d3THThalamus7.1
7.94
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018