AutismKB 2.0

Annotation Detail for NRN1L


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Basic Information Top
Gene Symbol:NRN1L ( MGC118990,MGC118993,UNQ2446 )
Gene Full Name: neuritin 1-like
Band: 16q22.1
Quick LinksEntrez ID:123904; OMIM: NA; Uniprot ID:NRN1L_HUMAN; ENSEMBL ID: ENSG00000188038; HGNC ID: 29811
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult3 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal10 / 33603072
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6072_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.24 ± 0.92
Basal Forebrain3.64 ± 0.63
Basal Part of Pons4.12 ± 0.52
Cerebellar Cortex3.5 ± 0.59
Cerebellar Nuclei2.98 ± 0.68
Claustrum3.62 ± 0.68
Epithalamus3.48 ± 0.86
Frontal Lobe3.19 ± 0.67
Globus Pallidus3.28 ± 0.64
Hypothalamus3.81 ± 0.53
Insula3.41 ± 0.41
Limbic Lobe3.12 ± 0.58
Mesencephalon3.2 ± 0.6
Myelencephalon3.42 ± 0.7
Occipital Lobe3.28 ± 0.93
Parietal Lobe3.27 ± 0.64
Pontine Tegmentum3.09 ± 0.59
Striatum4.65 ± 0.66
Subthalamus3.49 ± 0.31
Temporal Lobe3.22 ± 0.53
Thalamus3.52 ± 0.64
White Matter3.34 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
G630049C14RikCBCerebellum0.36
0.8
G630049C14RikCTXCerebral cortex0.42
0.62
G630049C14RikHIPHippocampal region0.12
0.18
G630049C14RikHPFHippocampal formation0.15
0.19
G630049C14RikHYHypothalamus0
0
G630049C14RikLSXLateral septal complex0
0
G630049C14RikMBMidbrain0.17
0.3
G630049C14RikMYMedulla0.3
0.3
G630049C14RikOLFOlfactory bulb0.17
0.19
G630049C14RikPPons0.19
0.46
G630049C14RikPALPallidum0.06
0.09
G630049C14RikRHPRetrohippocampal region0.17
0.19
G630049C14RiksAMYStriatum-like amygdalar nuclei0.26
0.25
G630049C14RikSTRStriatum0.21
0.17
G630049C14RikSTRdStriatum dorsal region0.19
0.15
G630049C14RikSTRvStriatum ventral region0.34
0.24
G630049C14RikTHThalamus0.14
0.23
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018