AutismKB 2.0

Annotation Detail for ADH1A


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Basic Information Top
Gene Symbol:ADH1A ( ADH1 )
Gene Full Name: alcohol dehydrogenase 1A (class I), alpha polypeptide
Band: 4q23
Quick LinksEntrez ID:124; OMIM: 103700; Uniprot ID:ADH1A_HUMAN; ENSEMBL ID: ENSG00000187758; HGNC ID: 249
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal102 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor29 / 125191231
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue29 / 149255194
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver100 / 207743481
lung0 / 3369740 
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207820_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.9
Adipocyte7.95
AdrenalCortex13.45
Adrenalgland7.2
Amygdala7.35
Appendix28.85
AtrioventricularNode12.15
BDCA4+_DentriticCells8.1
Bonemarrow8.7
BronchialEpithelialCells7.15
CD105+_Endothelial8.2
CD14+_Monocytes8.2
CD19+_BCells(neg._sel.)9.35
CD33+_Myeloid13.3
CD34+9.45
CD4+_Tcells7.45
CD56+_NKCells8.45
CD71+_EarlyErythroid7.6
CD8+_Tcells7
CardiacMyocytes11.4
Caudatenucleus7.1
Cerebellum6.5
CerebellumPeduncles9.85
CiliaryGanglion11.7
CingulateCortex8.8
Colorectaladenocarcinoma7.5
DorsalRootGanglion13.1
FetalThyroid8.15
Fetalbrain7.35
Fetalliver873
Fetallung6.25
GlobusPallidus6.3
Heart11.3
Hypothalamus7.8
Kidney7
Leukemia_chronicMyelogenousK-5627.05
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6
Liver811.95
Lung8.5
Lymphnode9
Lymphoma_burkitts(Daudi)11.2
Lymphoma_burkitts(Raji)12.6
MedullaOblongata8.65
OccipitalLobe6.8
OlfactoryBulb6.35
Ovary12.5
Pancreas6.5
PancreaticIslet8.85
ParietalLobe9.35
Pituitary9.25
Placenta7.95
Pons9.1
PrefrontalCortex9.5
Prostate8.6
Salivarygland13.15
SkeletalMuscle41.95
Skin13.45
SmoothMuscle8.55
Spinalcord8.5
SubthalamicNucleus8.1
SuperiorCervicalGanglion25.75
TemporalLobe10.95
Testis6.6
TestisGermCell6.25
TestisIntersitial6.6
TestisLeydigCell9.6
TestisSeminiferousTubule7.35
Thalamus8.25
Thymus5.75
Thyroid9.15
Tongue11.55
Tonsil8.45
Trachea6.5
TrigeminalGanglion17.65
Uterus6.25
UterusCorpus12.1
WholeBlood8.25
Wholebrain5.65
colon13.5
pineal_day13.38
pineal_night13.96
retina10.075
small_intestine11.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P291658
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 0.96
Basal Forebrain1.98 ± 0.23
Basal Part of Pons1.63 ± 0.32
Cerebellar Cortex1.75 ± 0.66
Cerebellar Nuclei2.25 ± 0.69
Claustrum2.79 ± 0.81
Epithalamus1.66 ± 0.76
Frontal Lobe1.81 ± 0.65
Globus Pallidus2.52 ± 0.26
Hypothalamus2.05 ± 0.56
Insula1.86 ± 0.49
Limbic Lobe1.95 ± 0.59
Mesencephalon2.11 ± 0.66
Myelencephalon1.98 ± 0.65
Occipital Lobe1.97 ± 0.54
Parietal Lobe1.92 ± 0.64
Pontine Tegmentum2.02 ± 0.66
Striatum2.15 ± 0.53
Subthalamus2.14 ± 0.66
Temporal Lobe1.87 ± 0.59
Thalamus1.93 ± 0.53
White Matter2.76 ± 0.78
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00150809 8 249 256 KPIQEVLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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