AutismKB 2.0

Annotation Detail for LTB4R


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Basic Information Top
Gene Symbol:LTB4R ( BLT1,BLTR,CMKRL1,GPR16,LTB4R1,LTBR1,P2RY7,P2Y7 )
Gene Full Name: leukotriene B4 receptor
Band: 14q12
Quick LinksEntrez ID:1241; OMIM: 601531; Uniprot ID:LT4R1_HUMAN; ENSEMBL ID: ENSG00000213903; HGNC ID: 6713
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor17 / 103127164
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal33 / 33603079
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood9 / 12347872
bone0 / 716550 
bone marrow3 / 4880161
brain2 / 11009891
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine2 / 2344728
kidney3 / 21177714
larynx2 / 2414582
liver0 / 2077430 
lung18 / 33697453
lymph0 / 442700 
lymph node3 / 9161032
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen3 / 5395255
stomach0 / 966190 
testis0 / 3304420 
thymus2 / 8113124
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220130_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.6
Adipocyte5.55
AdrenalCortex5.95
Adrenalgland4.75
Amygdala5.65
Appendix5.55
AtrioventricularNode4.3
BDCA4+_DentriticCells5.85
Bonemarrow7.15
BronchialEpithelialCells5.3
CD105+_Endothelial5.7
CD14+_Monocytes6
CD19+_BCells(neg._sel.)6
CD33+_Myeloid7.2
CD34+7.1
CD4+_Tcells6.1
CD56+_NKCells6.65
CD71+_EarlyErythroid5.3
CD8+_Tcells5.35
CardiacMyocytes6.95
Caudatenucleus6.2
Cerebellum4.55
CerebellumPeduncles6.4
CiliaryGanglion6.6
CingulateCortex6.15
Colorectaladenocarcinoma5.65
DorsalRootGanglion4.4
FetalThyroid5.45
Fetalbrain5.65
Fetalliver4.85
Fetallung4.4
GlobusPallidus4.15
Heart7.05
Hypothalamus6.1
Kidney6.3
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-604.95
Leukemialymphoblastic(MOLT-4)4.55
Liver7.4
Lung6.15
Lymphnode4.85
Lymphoma_burkitts(Daudi)7.15
Lymphoma_burkitts(Raji)7.8
MedullaOblongata5.9
OccipitalLobe6.35
OlfactoryBulb4.45
Ovary3.65
Pancreas4.5
PancreaticIslet6
ParietalLobe5.95
Pituitary6.6
Placenta5.85
Pons5.85
PrefrontalCortex7
Prostate6.3
Salivarygland4.5
SkeletalMuscle6.65
Skin4.45
SmoothMuscle6.4
Spinalcord6.05
SubthalamicNucleus6.5
SuperiorCervicalGanglion6.7
TemporalLobe10.65
Testis4.8
TestisGermCell4.4
TestisIntersitial4.65
TestisLeydigCell5.55
TestisSeminiferousTubule4.85
Thalamus9.5
Thymus4.15
Thyroid6.9
Tongue6.1
Tonsil6.6
Trachea6.85
TrigeminalGanglion5.65
Uterus4.35
UterusCorpus5.05
WholeBlood6.1
Wholebrain4.7
colon5.65
pineal_day6.74
pineal_night6.68
retina7.8
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P121030
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.43 ± 0.45
Basal Forebrain5.58 ± 0.31
Basal Part of Pons5.04 ± 0.29
Cerebellar Cortex4.94 ± 0.38
Cerebellar Nuclei5.29 ± 0.34
Claustrum5.39 ± 0.52
Epithalamus4.86 ± 0.45
Frontal Lobe5.04 ± 0.45
Globus Pallidus5.14 ± 0.56
Hypothalamus4.95 ± 0.49
Insula5.12 ± 0.35
Limbic Lobe5.34 ± 0.54
Mesencephalon5.28 ± 0.54
Myelencephalon5.23 ± 0.56
Occipital Lobe5.75 ± 0.56
Parietal Lobe5.22 ± 0.47
Pontine Tegmentum5.21 ± 0.51
Striatum6.01 ± 0.35
Subthalamus5.21 ± 0.35
Temporal Lobe5.06 ± 0.55
Thalamus5.21 ± 0.42
White Matter5.82 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ltb4r1CBCerebellum2.33
3.51
Ltb4r1CTXCerebral cortex5.87
4.34
Ltb4r1HIPHippocampal region6.58
6.19
Ltb4r1HPFHippocampal formation7.41
6.66
Ltb4r1HYHypothalamus5.04
3.71
Ltb4r1LSXLateral septal complex0.13
0.18
Ltb4r1MBMidbrain3.37
4.11
Ltb4r1MYMedulla0.75
1.27
Ltb4r1OLFOlfactory bulb1.59
1.49
Ltb4r1PPons3.98
6.19
Ltb4r1PALPallidum1.6
1.34
Ltb4r1RHPRetrohippocampal region8.75
7.26
Ltb4r1sAMYStriatum-like amygdalar nuclei1.54
0.93
Ltb4r1STRStriatum1.08
0.86
Ltb4r1STRdStriatum dorsal region1.31
1.11
Ltb4r1STRvStriatum ventral region0.42
0.3
Ltb4r1THThalamus6.77
5.5
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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