AutismKB 2.0

Annotation Detail for IQCK


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Basic Information Top
Gene Symbol:IQCK ( FLJ20115,FLJ36575,MGC35048 )
Gene Full Name: IQ motif containing K
Band: 16p12.3
Quick LinksEntrez ID:124152; OMIM: NA; Uniprot ID:IQCK_HUMAN; ENSEMBL ID: ENSG00000174628; HGNC ID: 28556
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult89 / 193912145
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal114 / 336030733
ovarian tumor4 / 7668252
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor25 / 125191199
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain34 / 110098930
cervix0 / 481710 
connective tissue28 / 149255187
ear1 / 1621261
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney14 / 21177766
larynx0 / 241450 
liver4 / 20774319
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas7 / 21481232
parathyroid4 / 20539194
pharynx3 / 4132872
pituitary gland2 / 16585120
placenta6 / 28082521
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis35 / 330442105
thymus0 / 811310 
thyroid6 / 47473126
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215130_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.4
Adipocyte17.25
AdrenalCortex24.15
Adrenalgland18.9
Amygdala19.4
Appendix33.5
AtrioventricularNode14.5
BDCA4+_DentriticCells10.55
Bonemarrow23.8
BronchialEpithelialCells15.85
CD105+_Endothelial12.75
CD14+_Monocytes13.6
CD19+_BCells(neg._sel.)15.95
CD33+_Myeloid18.3
CD34+12.85
CD4+_Tcells10.2
CD56+_NKCells12.45
CD71+_EarlyErythroid12
CD8+_Tcells9.05
CardiacMyocytes24.4
Caudatenucleus17.45
Cerebellum18.25
CerebellumPeduncles22.65
CiliaryGanglion16.2
CingulateCortex23.4
Colorectaladenocarcinoma18.45
DorsalRootGanglion17.25
FetalThyroid20.25
Fetalbrain17.3
Fetalliver16
Fetallung17.1
GlobusPallidus14.7
Heart29.3
Hypothalamus18.45
Kidney17.65
Leukemia_chronicMyelogenousK-56217.2
Leukemia_promyelocytic-HL-6013.65
Leukemialymphoblastic(MOLT-4)14.85
Liver34.05
Lung20.25
Lymphnode15.9
Lymphoma_burkitts(Daudi)23.8
Lymphoma_burkitts(Raji)29.75
MedullaOblongata20.7
OccipitalLobe17.35
OlfactoryBulb14.65
Ovary15
Pancreas15.2
PancreaticIslet19.7
ParietalLobe22.05
Pituitary29.1
Placenta16.75
Pons25.3
PrefrontalCortex16.65
Prostate18.85
Salivarygland15.3
SkeletalMuscle25.1
Skin18.2
SmoothMuscle20.2
Spinalcord19.85
SubthalamicNucleus16.25
SuperiorCervicalGanglion32.95
TemporalLobe17.15
Testis63.75
TestisGermCell21.3
TestisIntersitial22.35
TestisLeydigCell33.85
TestisSeminiferousTubule26.75
Thalamus18.7
Thymus14.6
Thyroid21.3
Tongue27.55
Tonsil20.95
Trachea27.9
TrigeminalGanglion32.95
Uterus14.75
UterusCorpus23
WholeBlood18.2
Wholebrain16.2
colon24.5
pineal_day24.36
pineal_night17.08
retina22.85
small_intestine17.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_31_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.42
Basal Forebrain6.41 ± 0.21
Basal Part of Pons6.08 ± 0.33
Cerebellar Cortex5.85 ± 0.2
Cerebellar Nuclei5.75 ± 0.43
Claustrum5.74 ± 0.42
Epithalamus7.19 ± 0.65
Frontal Lobe6.08 ± 0.47
Globus Pallidus7.25 ± 0.2
Hypothalamus6.48 ± 0.31
Insula6.23 ± 0.33
Limbic Lobe6.22 ± 0.46
Mesencephalon6.24 ± 0.4
Myelencephalon6.21 ± 0.47
Occipital Lobe6.14 ± 0.36
Parietal Lobe6.19 ± 0.34
Pontine Tegmentum6.14 ± 0.52
Striatum6.7 ± 0.36
Subthalamus6.05 ± 0.39
Temporal Lobe6.09 ± 0.35
Thalamus6.1 ± 0.27
White Matter6.98 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
IqckCBCerebellum0.62
0.9
IqckCTXCerebral cortex0.89
0.91
IqckHIPHippocampal region0.47
0.61
IqckHPFHippocampal formation0.63
0.71
IqckHYHypothalamus1.95
2.86
IqckLSXLateral septal complex0
0
IqckMBMidbrain0.33
0.56
IqckMYMedulla1.43
1.88
IqckOLFOlfactory bulb3.96
4.76
IqckPPons0.37
0.58
IqckPALPallidum0.21
0.48
IqckRHPRetrohippocampal region0.91
0.86
IqcksAMYStriatum-like amygdalar nuclei0.44
0.44
IqckSTRStriatum0.19
0.25
IqckSTRdStriatum dorsal region0.18
0.24
IqckSTRvStriatum ventral region0.21
0.3
IqckTHThalamus2.35
3.58
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01039377 11 159 169 RKRTKFIACDF Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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