AutismKB 2.0

Annotation Detail for ABCC2


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Basic Information Top
Gene Symbol:ABCC2 ( ABC30,CMOAT,DJS,KIAA1010,MRP2,cMRP )
Gene Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Band: 10q24.2
Quick LinksEntrez ID:1244; OMIM: 601107; Uniprot ID:MRP2_HUMAN; ENSEMBL ID: ENSG00000023839; HGNC ID: 53
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal53 / 336030715
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain2 / 11009891
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine1 / 2344724
kidney10 / 21177747
larynx0 / 241450 
liver23 / 207743110
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach4 / 9661941
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206155_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte11.2
AdrenalCortex7.2
Adrenalgland5.25
Amygdala6.25
Appendix6.5
AtrioventricularNode5.45
BDCA4+_DentriticCells6.2
Bonemarrow6.35
BronchialEpithelialCells6
CD105+_Endothelial5.9
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.4
CD33+_Myeloid7.45
CD34+7.45
CD4+_Tcells6.2
CD56+_NKCells6.6
CD71+_EarlyErythroid5.8
CD8+_Tcells5.4
CardiacMyocytes8.25
Caudatenucleus5.5
Cerebellum8
CerebellumPeduncles7.15
CiliaryGanglion4.8
CingulateCortex6.35
Colorectaladenocarcinoma5.95
DorsalRootGanglion5.1
FetalThyroid5.95
Fetalbrain6.25
Fetalliver15.15
Fetallung12.95
GlobusPallidus4.6
Heart8.05
Hypothalamus6.5
Kidney9.45
Leukemia_chronicMyelogenousK-5625.6
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)4.85
Liver8.85
Lung7.05
Lymphnode5.95
Lymphoma_burkitts(Daudi)8
Lymphoma_burkitts(Raji)9.15
MedullaOblongata5.65
OccipitalLobe5.55
OlfactoryBulb5.35
Ovary4.3
Pancreas12.05
PancreaticIslet23.1
ParietalLobe6.8
Pituitary7.25
Placenta6.4
Pons5.95
PrefrontalCortex7.35
Prostate7.1
Salivarygland5.25
SkeletalMuscle8.65
Skin5.25
SmoothMuscle7
Spinalcord6.6
SubthalamicNucleus6.3
SuperiorCervicalGanglion8.85
TemporalLobe5.6
Testis5.35
TestisGermCell5.2
TestisIntersitial5.2
TestisLeydigCell6.2
TestisSeminiferousTubule5.3
Thalamus6.3
Thymus4.8
Thyroid7.5
Tongue6.35
Tonsil6.05
Trachea5.2
TrigeminalGanglion6.8
Uterus4.9
UterusCorpus5.9
WholeBlood6.75
Wholebrain5.25
colon6.05
pineal_day7.32
pineal_night6.92
retina7.475
small_intestine6.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P44569
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.71 ± 0.95
Basal Forebrain2.14 ± 0.18
Basal Part of Pons2.26 ± 0.67
Cerebellar Cortex2.45 ± 0.8
Cerebellar Nuclei2.52 ± 0.63
Claustrum3.23 ± 0.89
Epithalamus2.28 ± 0.75
Frontal Lobe2.2 ± 0.68
Globus Pallidus2.76 ± 0.64
Hypothalamus2.49 ± 0.86
Insula2.34 ± 0.61
Limbic Lobe2.52 ± 0.67
Mesencephalon2.61 ± 0.84
Myelencephalon2.43 ± 0.68
Occipital Lobe2.44 ± 0.82
Parietal Lobe2.47 ± 0.81
Pontine Tegmentum2.48 ± 0.71
Striatum2.56 ± 0.73
Subthalamus2.52 ± 0.73
Temporal Lobe2.34 ± 0.74
Thalamus2.33 ± 0.69
White Matter2.68 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abcc2CBCerebellum20.95
20.94
Abcc2CTXCerebral cortex10.69
7.36
Abcc2HIPHippocampal region9.62
8.99
Abcc2HPFHippocampal formation9.62
8.18
Abcc2HYHypothalamus10.27
7.84
Abcc2LSXLateral septal complex7.72
4.79
Abcc2MBMidbrain13.5
12.09
Abcc2MYMedulla29
30.87
Abcc2OLFOlfactory bulb17.07
13.03
Abcc2PPons25.22
24.34
Abcc2PALPallidum12.93
12.13
Abcc2RHPRetrohippocampal region9.49
6.83
Abcc2sAMYStriatum-like amygdalar nuclei8.28
6.61
Abcc2STRStriatum5.88
4.27
Abcc2STRdStriatum dorsal region6.02
4.47
Abcc2STRvStriatum ventral region3.71
2.46
Abcc2THThalamus23.77
20.06
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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