AutismKB 2.0

Annotation Detail for ANKS3


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Basic Information Top
Gene Symbol:ANKS3 ( FLJ32345,FLJ32767,KIAA1977 )
Gene Full Name: ankyrin repeat and sterile alpha motif domain containing 3
Band: 16p13.3
Quick LinksEntrez ID:124401; OMIM: NA; Uniprot ID:ANKS3_HUMAN; ENSEMBL ID: ENSG00000168096; HGNC ID: 29422
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal100 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone2 / 7165527
bone marrow0 / 488010 
brain41 / 110098937
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus2 / 2020998
eye4 / 21105418
heart0 / 896260 
intestine3 / 23447212
kidney2 / 2117779
larynx0 / 241450 
liver2 / 2077439
lung6 / 33697417
lymph0 / 442700 
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary2 / 10205119
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta14 / 28082549
prostate7 / 18934536
salivary gland1 / 2015549
skin1 / 2105744
spleen1 / 5395218
stomach4 / 9661941
testis11 / 33044233
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_501_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.65 ± 0.56
Basal Forebrain4.58 ± 0.3
Basal Part of Pons4.35 ± 0.43
Cerebellar Cortex4.56 ± 0.41
Cerebellar Nuclei4.34 ± 0.57
Claustrum5.02 ± 0.69
Epithalamus4.11 ± 0.26
Frontal Lobe4.2 ± 0.45
Globus Pallidus4.67 ± 0.36
Hypothalamus4.51 ± 0.42
Insula4.37 ± 0.34
Limbic Lobe4.49 ± 0.59
Mesencephalon4.52 ± 0.62
Myelencephalon4.48 ± 0.59
Occipital Lobe4.89 ± 0.52
Parietal Lobe4.52 ± 0.49
Pontine Tegmentum4.54 ± 0.55
Striatum4.38 ± 0.61
Subthalamus4.24 ± 0.64
Temporal Lobe4.44 ± 0.58
Thalamus4.49 ± 0.42
White Matter4.84 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anks3CBCerebellum14.71
13.49
Anks3CTXCerebral cortex47.54
30.32
Anks3HIPHippocampal region39.32
39.13
Anks3HPFHippocampal formation41.71
35.94
Anks3HYHypothalamus22.86
15.48
Anks3LSXLateral septal complex27.54
17.21
Anks3MBMidbrain24.01
17.88
Anks3MYMedulla23.97
20.81
Anks3OLFOlfactory bulb51.19
37.68
Anks3PPons25.05
20.25
Anks3PALPallidum21.28
14.9
Anks3RHPRetrohippocampal region46.07
32.29
Anks3sAMYStriatum-like amygdalar nuclei22.87
14.46
Anks3STRStriatum22.03
13.68
Anks3STRdStriatum dorsal region18.85
11.84
Anks3STRvStriatum ventral region29.9
17.32
Anks3THThalamus21.45
14.15
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ANKS3_HUMAN_2 15 2 16 SELSDEASEPELLNR PRIDE
PAp00032551 21 360 380 AQGLSSEASVESNEDSDHACK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018