AutismKB 2.0

Annotation Detail for SEPT12


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Basic Information Top
Gene Symbol:SEPT12 ( FLJ25410 )
Gene Full Name: septin 12
Band: 16p13.3
Quick LinksEntrez ID:124404; OMIM: 611562; Uniprot ID:SEP12_HUMAN; ENSEMBL ID: ENSG00000140623; HGNC ID: 26348
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult8 / 19391214
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal26 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis23 / 33044269
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P89101
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.11 ± 0.71
Basal Forebrain4.6 ± 0.6
Basal Part of Pons4.69 ± 0.55
Cerebellar Cortex5.29 ± 0.41
Cerebellar Nuclei5.16 ± 0.63
Claustrum4.49 ± 0.75
Epithalamus4.39 ± 0.43
Frontal Lobe4.36 ± 0.65
Globus Pallidus4.89 ± 0.83
Hypothalamus4.2 ± 0.61
Insula4.08 ± 0.28
Limbic Lobe4.29 ± 0.7
Mesencephalon4.55 ± 0.81
Myelencephalon4.6 ± 0.72
Occipital Lobe5.13 ± 0.69
Parietal Lobe4.4 ± 0.7
Pontine Tegmentum4.48 ± 0.7
Striatum4.81 ± 0.91
Subthalamus4.57 ± 0.72
Temporal Lobe4.24 ± 0.72
Thalamus4.56 ± 0.56
White Matter6.57 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4933413B09RikCBCerebellum0.44
0.57
4933413B09RikCTXCerebral cortex0.26
0.38
4933413B09RikHIPHippocampal region0.15
0.14
4933413B09RikHPFHippocampal formation0.21
0.28
4933413B09RikHYHypothalamus0.07
0.09
4933413B09RikLSXLateral septal complex0
0
4933413B09RikMBMidbrain0.26
0.48
4933413B09RikMYMedulla0.32
0.42
4933413B09RikOLFOlfactory bulb0.16
0.23
4933413B09RikPPons0.08
0.07
4933413B09RikPALPallidum0.06
0.29
4933413B09RikRHPRetrohippocampal region0.32
0.46
4933413B09RiksAMYStriatum-like amygdalar nuclei0.26
0.39
4933413B09RikSTRStriatum0.12
0.13
4933413B09RikSTRdStriatum dorsal region0.12
0.14
4933413B09RikSTRvStriatum ventral region0.07
0.04
4933413B09RikTHThalamus0.16
0.18
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018