AutismKB 2.0

Annotation Detail for ADH1B


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Basic Information Top
Gene Symbol:ADH1B ( ADH2,DKFZp686C06125 )
Gene Full Name: alcohol dehydrogenase 1B (class I), beta polypeptide
Band: 4q23
Quick LinksEntrez ID:125; OMIM: 103720; Uniprot ID:ADH1B_HUMAN; ENSEMBL ID: ENSG00000196616; HGNC ID: 250
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus24 / 56401242
neonate3 / 3109796
infant0 / 236200 
juvenile9 / 55556161
adult200 / 1939121103
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor3 / 17290173
gastrointestinal tumor5 / 11936941
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor79 / 96359819
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal627 / 3360307186
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue59 / 131064501
adrenal gland26 / 33197783
ascites0 / 400150 
bladder4 / 29757134
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain27 / 110098924
cervix2 / 4817141
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus9 / 20209445
eye2 / 2110549
heart54 / 89626602
intestine51 / 234472217
kidney9 / 21177742
larynx1 / 2414541
liver282 / 2077431357
lung55 / 336974163
lymph0 / 442700 
lymph node0 / 916100 
mammary gland77 / 153271502
mouth3 / 6705244
muscle12 / 107715111
nerve11 / 15768697
ovary0 / 1020510 
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx9 / 41328217
pituitary gland0 / 165850 
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin4 / 21057418
spleen25 / 53952463
stomach21 / 96619217
testis7 / 33044221
thymus10 / 81131123
thyroid0 / 474730 
tonsil0 / 169990 
trachea77 / 524131469
umbilical cord0 / 136800 
uterus57 / 232878244
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209612_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte1599
AdrenalCortex27.55
Adrenalgland146.55
Amygdala6.15
Appendix265.15
AtrioventricularNode71.45
BDCA4+_DentriticCells5.8
Bonemarrow6.9
BronchialEpithelialCells5.6
CD105+_Endothelial5.65
CD14+_Monocytes6.05
CD19+_BCells(neg._sel.)5.9
CD33+_Myeloid7.2
CD34+6.95
CD4+_Tcells6.2
CD56+_NKCells6.65
CD71+_EarlyErythroid5.65
CD8+_Tcells5.5
CardiacMyocytes8.2
Caudatenucleus5.25
Cerebellum4.75
CerebellumPeduncles6.6
CiliaryGanglion109.45
CingulateCortex6.2
Colorectaladenocarcinoma5.95
DorsalRootGanglion29.35
FetalThyroid10.8
Fetalbrain6
Fetalliver14.8
Fetallung339.55
GlobusPallidus4.6
Heart13.45
Hypothalamus6.1
Kidney12.6
Leukemia_chronicMyelogenousK-5625.35
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.7
Liver913.1
Lung162.2
Lymphnode119.45
Lymphoma_burkitts(Daudi)7.55
Lymphoma_burkitts(Raji)9
MedullaOblongata5.25
OccipitalLobe5.3
OlfactoryBulb37.9
Ovary178.1
Pancreas13.55
PancreaticIslet25.4
ParietalLobe6.3
Pituitary11.3
Placenta6.1
Pons5.65
PrefrontalCortex7.35
Prostate7.25
Salivarygland122.7
SkeletalMuscle17
Skin70.85
SmoothMuscle6.65
Spinalcord7.95
SubthalamicNucleus5.8
SuperiorCervicalGanglion10.35
TemporalLobe5.35
Testis5.05
TestisGermCell8.1
TestisIntersitial5.55
TestisLeydigCell6.85
TestisSeminiferousTubule5.65
Thalamus6.2
Thymus21.6
Thyroid39.95
Tongue19.35
Tonsil5.75
Trachea126.65
TrigeminalGanglion35.85
Uterus240.3
UterusCorpus6.4
WholeBlood6.35
Wholebrain4.5
colon615.45
pineal_day7.34
pineal_night7.34
retina11.45
small_intestine755.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16739_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.4 ± 0.97
Basal Forebrain2 ± 0.18
Basal Part of Pons1.72 ± 0.38
Cerebellar Cortex1.83 ± 0.67
Cerebellar Nuclei2.26 ± 0.68
Claustrum2.87 ± 0.83
Epithalamus1.69 ± 0.7
Frontal Lobe1.85 ± 0.61
Globus Pallidus2.58 ± 0.34
Hypothalamus2.17 ± 0.86
Insula1.91 ± 0.53
Limbic Lobe1.97 ± 0.59
Mesencephalon2.14 ± 0.67
Myelencephalon2.02 ± 0.65
Occipital Lobe2.01 ± 0.58
Parietal Lobe1.97 ± 0.64
Pontine Tegmentum2.03 ± 0.61
Striatum2.18 ± 0.54
Subthalamus2.1 ± 0.6
Temporal Lobe1.9 ± 0.6
Thalamus2 ± 0.55
White Matter2.57 ± 0.36
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079877 12 103 114 VCKNPESNYCLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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