AutismKB 2.0

Annotation Detail for TBC1D16


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Basic Information Top
Gene Symbol:TBC1D16 ( FLJ20748,MGC25062 )
Gene Full Name: TBC1 domain family, member 16
Band: 17q25.3
Quick LinksEntrez ID:125058; OMIM: NA; Uniprot ID:TBC16_HUMAN; ENSEMBL ID: ENSG00000167291; HGNC ID: 28356
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus35 / 56401262
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult100 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor20 / 94178212
cervical tumor1 / 3436629
chondrosarcoma8 / 8282396
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor15 / 26384556
glioma14 / 106883130
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor8 / 10312777
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal139 / 336030741
ovarian tumor3 / 7668239
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma6 / 46356129
skin tumor70 / 124949560
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder4 / 29757134
blood5 / 12347840
bone7 / 7165597
bone marrow0 / 488010 
brain41 / 110098937
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye22 / 211054104
heart11 / 89626122
intestine18 / 23447276
kidney12 / 21177756
larynx1 / 2414541
liver3 / 20774314
lung12 / 33697435
lymph0 / 442700 
lymph node1 / 9161010
mammary gland23 / 153271150
mouth2 / 6705229
muscle4 / 10771537
nerve1 / 1576863
ovary5 / 10205148
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate6 / 18934531
salivary gland0 / 201550 
skin78 / 210574370
spleen2 / 5395237
stomach2 / 9661920
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord6 / 13680438
uterus23 / 23287898
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1018_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.85 ± 0.7
Basal Forebrain3.93 ± 0.61
Basal Part of Pons3.48 ± 0.63
Cerebellar Cortex4.05 ± 0.42
Cerebellar Nuclei3.71 ± 0.41
Claustrum3.78 ± 0.68
Epithalamus3.24 ± 0.65
Frontal Lobe3.55 ± 0.7
Globus Pallidus3.49 ± 0.89
Hypothalamus3.41 ± 0.63
Insula3.57 ± 0.5
Limbic Lobe3.69 ± 0.7
Mesencephalon3.78 ± 0.62
Myelencephalon3.91 ± 0.66
Occipital Lobe4.17 ± 0.67
Parietal Lobe3.81 ± 0.54
Pontine Tegmentum3.75 ± 0.84
Striatum4.57 ± 0.69
Subthalamus3.23 ± 0.84
Temporal Lobe3.66 ± 0.63
Thalamus4.14 ± 0.53
White Matter3.83 ± 0.74
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tbc1d16CBCerebellum5.46
5.21
Tbc1d16CTXCerebral cortex1.11
1.01
Tbc1d16HIPHippocampal region2.17
1.93
Tbc1d16HPFHippocampal formation1.73
1.52
Tbc1d16HYHypothalamus1.62
1.5
Tbc1d16LSXLateral septal complex1.23
0.84
Tbc1d16MBMidbrain1.16
1.24
Tbc1d16MYMedulla1.33
1.29
Tbc1d16OLFOlfactory bulb3.59
2.6
Tbc1d16PPons0.85
0.64
Tbc1d16PALPallidum4.45
4.09
Tbc1d16RHPRetrohippocampal region0.71
0.79
Tbc1d16sAMYStriatum-like amygdalar nuclei1.44
1.12
Tbc1d16STRStriatum3.65
2.41
Tbc1d16STRdStriatum dorsal region3.15
2.04
Tbc1d16STRvStriatum ventral region7.63
4.79
Tbc1d16THThalamus1.74
1.27
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018