AutismKB 2.0

Annotation Detail for ADH1C


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Basic Information Top
Gene Symbol:ADH1C ( ADH3 )
Gene Full Name: alcohol dehydrogenase 1C (class I), gamma polypeptide
Band: 4q23
Quick LinksEntrez ID:126; OMIM: 103730; Uniprot ID:ADH1G_HUMAN; ENSEMBL ID: ENSG00000248144; HGNC ID: 251
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus1 / 5640121
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult26 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain1 / 11009890 
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine72 / 234472307
kidney2 / 2117779
larynx0 / 241450 
liver38 / 207743182
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach7 / 9661972
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206262_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.6
Adipocyte17.7
AdrenalCortex15.6
Adrenalgland10.3
Amygdala9.85
Appendix38.3
AtrioventricularNode21.45
BDCA4+_DentriticCells9.05
Bonemarrow14.7
BronchialEpithelialCells10.55
CD105+_Endothelial11.1
CD14+_Monocytes11.35
CD19+_BCells(neg._sel.)10.25
CD33+_Myeloid11.95
CD34+11.6
CD4+_Tcells11.15
CD56+_NKCells11.95
CD71+_EarlyErythroid10.7
CD8+_Tcells8.05
CardiacMyocytes24.6
Caudatenucleus9.95
Cerebellum9.1
CerebellumPeduncles14.55
CiliaryGanglion13.45
CingulateCortex11.65
Colorectaladenocarcinoma10.8
DorsalRootGanglion11.9
FetalThyroid11.85
Fetalbrain10.85
Fetalliver15.15
Fetallung14.3
GlobusPallidus9.25
Heart16
Hypothalamus10.75
Kidney11
Leukemia_chronicMyelogenousK-56210.1
Leukemia_promyelocytic-HL-609.7
Leukemialymphoblastic(MOLT-4)8.75
Liver762.55
Lung12.3
Lymphnode11.45
Lymphoma_burkitts(Daudi)14.85
Lymphoma_burkitts(Raji)17.25
MedullaOblongata11.1
OccipitalLobe9.6
OlfactoryBulb10.85
Ovary17.2
Pancreas10.95
PancreaticIslet12.2
ParietalLobe13.45
Pituitary13.2
Placenta10.15
Pons14.1
PrefrontalCortex12.7
Prostate12.3
Salivarygland12.2
SkeletalMuscle25.7
Skin12.7
SmoothMuscle12.55
Spinalcord12.8
SubthalamicNucleus12.2
SuperiorCervicalGanglion19.85
TemporalLobe10.6
Testis9.55
TestisGermCell8.95
TestisIntersitial9.35
TestisLeydigCell10.9
TestisSeminiferousTubule9.6
Thalamus11.85
Thymus7.9
Thyroid12.85
Tongue14.35
Tonsil10.8
Trachea19.75
TrigeminalGanglion15.55
Uterus9.05
UterusCorpus23.9
WholeBlood11.3
Wholebrain8.5
colon1050.35
pineal_day11.94
pineal_night11.62
retina12.85
small_intestine702.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P81158
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.7 ± 0.6
Basal Forebrain3.92 ± 0.43
Basal Part of Pons2.88 ± 0.73
Cerebellar Cortex3.15 ± 0.69
Cerebellar Nuclei3.82 ± 0.6
Claustrum4.06 ± 0.99
Epithalamus2.53 ± 0.74
Frontal Lobe3.63 ± 0.9
Globus Pallidus4.43 ± 0.42
Hypothalamus3.27 ± 0.87
Insula2.99 ± 0.55
Limbic Lobe3.68 ± 0.87
Mesencephalon3.86 ± 0.79
Myelencephalon3.75 ± 0.77
Occipital Lobe3.59 ± 0.83
Parietal Lobe3.51 ± 0.85
Pontine Tegmentum3.68 ± 0.78
Striatum4.07 ± 0.8
Subthalamus3.84 ± 0.49
Temporal Lobe3.46 ± 0.78
Thalamus3.75 ± 0.74
White Matter3.83 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adh1CBCerebellum0.66
1.28
Adh1CTXCerebral cortex0.62
0.78
Adh1HIPHippocampal region1.08
1.86
Adh1HPFHippocampal formation1.16
1.66
Adh1HYHypothalamus0.68
1.07
Adh1LSXLateral septal complex0
0
Adh1MBMidbrain0.57
1.77
Adh1MYMedulla1.52
4.46
Adh1OLFOlfactory bulb1.33
2.08
Adh1PPons1.54
5.44
Adh1PALPallidum0.34
0.57
Adh1RHPRetrohippocampal region1.24
0.99
Adh1sAMYStriatum-like amygdalar nuclei0.87
1.65
Adh1STRStriatum0.78
1.35
Adh1STRdStriatum dorsal region0.47
0.8
Adh1STRvStriatum ventral region0.41
0.27
Adh1THThalamus0.8
1.31
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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