AutismKB 2.0

Annotation Detail for C19orf28


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Basic Information Top
Gene Symbol:C19orf28 ( MGC20700,PP3501 )
Gene Full Name: chromosome 19 open reading frame 28
Band: 19p13.3
Quick LinksEntrez ID:126321; OMIM: NA; Uniprot ID:CS028_HUMAN; ENSEMBL ID: ENSG00000161091; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst3 / 6231948
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor25 / 26384594
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor12 / 103127116
lymphoma4 / 7175555
non-neoplasia2 / 9725020
normal107 / 336030731
ovarian tumor4 / 7668252
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor69 / 124949552
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone4 / 7165555
bone marrow1 / 4880120
brain23 / 110098920
cervix11 / 48171228
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine9 / 23447238
kidney19 / 21177789
larynx0 / 241450 
liver8 / 20774338
lung35 / 336974103
lymph0 / 442700 
lymph node1 / 9161010
mammary gland11 / 15327171
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary9 / 10205188
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate9 / 18934547
salivary gland1 / 2015549
skin77 / 210574365
spleen2 / 5395237
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid3 / 4747363
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220178_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.6
Adipocyte3.55
AdrenalCortex3.8
Adrenalgland3.05
Amygdala3.85
Appendix3.6
AtrioventricularNode2.8
BDCA4+_DentriticCells8.3
Bonemarrow3.55
BronchialEpithelialCells3.6
CD105+_Endothelial3.7
CD14+_Monocytes4.3
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid10.2
CD34+10.3
CD4+_Tcells11
CD56+_NKCells5.3
CD71+_EarlyErythroid3.35
CD8+_Tcells7.6
CardiacMyocytes4.65
Caudatenucleus3.25
Cerebellum2.95
CerebellumPeduncles4.1
CiliaryGanglion2.55
CingulateCortex3.7
Colorectaladenocarcinoma4.05
DorsalRootGanglion2.75
FetalThyroid3.5
Fetalbrain3.65
Fetalliver3.05
Fetallung3.05
GlobusPallidus2.7
Heart4.6
Hypothalamus4.45
Kidney6.5
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver4.75
Lung4
Lymphnode3.5
Lymphoma_burkitts(Daudi)4.65
Lymphoma_burkitts(Raji)6.1
MedullaOblongata3.35
OccipitalLobe3.25
OlfactoryBulb3.9
Ovary2.4
Pancreas2.95
PancreaticIslet3.85
ParietalLobe3.85
Pituitary4.25
Placenta3.8
Pons3.45
PrefrontalCortex5.1
Prostate5.15
Salivarygland2.9
SkeletalMuscle4.15
Skin2.75
SmoothMuscle4.45
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion4
TemporalLobe3.55
Testis3.1
TestisGermCell3.05
TestisIntersitial3.05
TestisLeydigCell3.55
TestisSeminiferousTubule3.1
Thalamus3.7
Thymus6.6
Thyroid4.5
Tongue3.55
Tonsil3.55
Trachea3
TrigeminalGanglion3.55
Uterus3.85
UterusCorpus3.25
WholeBlood3.9
Wholebrain3.8
colon3.65
pineal_day4.82
pineal_night4.82
retina4.425
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5335_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.5 ± 1.01
Basal Forebrain4.14 ± 0.43
Basal Part of Pons4.94 ± 0.69
Cerebellar Cortex4.19 ± 0.68
Cerebellar Nuclei4.18 ± 0.49
Claustrum3.78 ± 0.96
Epithalamus4.16 ± 0.93
Frontal Lobe5.01 ± 0.67
Globus Pallidus4.03 ± 0.63
Hypothalamus3.98 ± 0.59
Insula4.91 ± 0.53
Limbic Lobe4.87 ± 0.84
Mesencephalon4.61 ± 0.71
Myelencephalon4.6 ± 0.78
Occipital Lobe3.92 ± 0.96
Parietal Lobe4.63 ± 0.7
Pontine Tegmentum4.39 ± 0.61
Striatum3.87 ± 1
Subthalamus4.49 ± 0.82
Temporal Lobe4.98 ± 0.62
Thalamus4.55 ± 0.69
White Matter5.06 ± 0.61
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
F630110N24RikCBCerebellum24.27
37.71
F630110N24RikCTXCerebral cortex22.3
16
F630110N24RikHIPHippocampal region21.77
23.83
F630110N24RikHPFHippocampal formation18.78
18.2
F630110N24RikHYHypothalamus7.82
5.62
F630110N24RikLSXLateral septal complex4.21
2.65
F630110N24RikMBMidbrain13.88
13.18
F630110N24RikMYMedulla14.47
16.94
F630110N24RikOLFOlfactory bulb17.41
12.91
F630110N24RikPPons13.65
14.74
F630110N24RikPALPallidum4.64
4.07
F630110N24RikRHPRetrohippocampal region14.38
11.17
F630110N24RiksAMYStriatum-like amygdalar nuclei1.9
1.42
F630110N24RikSTRStriatum2.81
2.17
F630110N24RikSTRdStriatum dorsal region2.34
1.82
F630110N24RikSTRvStriatum ventral region4.27
3.38
F630110N24RikTHThalamus10.77
10.3
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00133703 26 244 269 RPHAEEPGEHTPLLAPATAQPLLLWK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018