AutismKB 2.0

Annotation Detail for CNN3


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Basic Information Top
Gene Symbol:CNN3 ( - )
Gene Full Name: calponin 3, acidic
Band: 1p21.3
Quick LinksEntrez ID:1266; OMIM: 602374; Uniprot ID:CNN3_HUMAN; ENSEMBL ID: ENSG00000117519; HGNC ID: 2157
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst10 / 62319160
fetus39 / 56401269
neonate12 / 31097385
infant6 / 23620254
juvenile3 / 5555653
adult191 / 193912198
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma4 / 17475228
breast (mammary gland) tumor6 / 9417863
cervical tumor3 / 3436687
chondrosarcoma8 / 8282396
colorectal tumor5 / 11424643
esophageal tumor10 / 17290578
gastrointestinal tumor8 / 11936967
germ cell tumor28 / 263845106
glioma16 / 106883149
head and neck tumor13 / 13630295
kidney tumor8 / 68959116
leukemia2 / 9584220
liver tumor10 / 96359103
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia18 / 97250185
normal405 / 3360307120
ovarian tumor3 / 7668239
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor31 / 124949248
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland16 / 33197481
ascites2 / 4001549
bladder13 / 29757436
blood1 / 1234788
bone10 / 71655139
bone marrow2 / 4880140
brain145 / 1100989131
cervix6 / 48171124
connective tissue9 / 14925560
ear6 / 16212370
embryonic tissue48 / 215722222
esophagus11 / 20209544
eye28 / 211054132
heart10 / 89626111
intestine15 / 23447263
kidney30 / 211777141
larynx6 / 24145248
liver15 / 20774372
lung44 / 336974130
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth2 / 6705229
muscle8 / 10771574
nerve6 / 15768380
ovary4 / 10205139
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta39 / 280825138
prostate11 / 18934558
salivary gland2 / 2015599
skin37 / 210574175
spleen0 / 539520 
stomach7 / 9661972
testis25 / 33044275
thymus4 / 8113149
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord10 / 13680730
uterus40 / 232878171
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201445_at
Cell line Expression level Expression bar
721_B_lymphoblasts215.05
Adipocyte252.85
AdrenalCortex57.8
Adrenalgland109.5
Amygdala160.95
Appendix41.75
AtrioventricularNode18
BDCA4+_DentriticCells4.75
Bonemarrow4.65
BronchialEpithelialCells123.9
CD105+_Endothelial9.6
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)5.5
CD33+_Myeloid6.45
CD34+6
CD4+_Tcells4.95
CD56+_NKCells5.9
CD71+_EarlyErythroid5.7
CD8+_Tcells4.35
CardiacMyocytes37.35
Caudatenucleus57.35
Cerebellum19.55
CerebellumPeduncles31.2
CiliaryGanglion22.15
CingulateCortex19
Colorectaladenocarcinoma4.55
DorsalRootGanglion32.25
FetalThyroid14.4
Fetalbrain126.85
Fetalliver17.6
Fetallung243.2
GlobusPallidus9.7
Heart6.15
Hypothalamus78.35
Kidney97.1
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)4.7
Liver13.5
Lung176.75
Lymphnode32.35
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)6.25
MedullaOblongata36.8
OccipitalLobe60.15
OlfactoryBulb209.75
Ovary79.95
Pancreas26.8
PancreaticIslet64.55
ParietalLobe17.2
Pituitary27.05
Placenta255.8
Pons28.6
PrefrontalCortex59.25
Prostate207.1
Salivarygland10.85
SkeletalMuscle14.25
Skin4.35
SmoothMuscle44.25
Spinalcord125.95
SubthalamicNucleus11.8
SuperiorCervicalGanglion14.4
TemporalLobe34.25
Testis20.65
TestisGermCell14.75
TestisIntersitial20.3
TestisLeydigCell26.45
TestisSeminiferousTubule21.05
Thalamus40.35
Thymus28.05
Thyroid158.05
Tongue15.2
Tonsil6.1
Trachea84.75
TrigeminalGanglion20.35
Uterus335.4
UterusCorpus44.05
WholeBlood5.15
Wholebrain83
colon217.95
pineal_day79.14
pineal_night54.84
retina403.425
small_intestine307.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P138168
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.77 ± 0.31
Basal Forebrain9.76 ± 0.22
Basal Part of Pons8.88 ± 0.25
Cerebellar Cortex8.95 ± 0.18
Cerebellar Nuclei9.09 ± 0.31
Claustrum9.35 ± 0.29
Epithalamus10.2 ± 0.31
Frontal Lobe9.27 ± 0.41
Globus Pallidus10.53 ± 0.39
Hypothalamus9.58 ± 0.39
Insula9.25 ± 0.36
Limbic Lobe9.29 ± 0.53
Mesencephalon9.6 ± 0.39
Myelencephalon9.47 ± 0.49
Occipital Lobe9.24 ± 0.41
Parietal Lobe9.29 ± 0.48
Pontine Tegmentum9.41 ± 0.36
Striatum9.99 ± 0.46
Subthalamus8.98 ± 0.17
Temporal Lobe9.31 ± 0.34
Thalamus9.48 ± 0.29
White Matter9.76 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cnn3CBCerebellum28.69
81.3
Cnn3CTXCerebral cortex17.42
14.44
Cnn3HIPHippocampal region30.07
42.83
Cnn3HPFHippocampal formation29.51
35.03
Cnn3HYHypothalamus8.47
7.56
Cnn3LSXLateral septal complex27
29.21
Cnn3MBMidbrain16.27
20.39
Cnn3MYMedulla39.89
51.48
Cnn3OLFOlfactory bulb60.59
70.05
Cnn3PPons29.47
35.41
Cnn3PALPallidum10.03
10.95
Cnn3RHPRetrohippocampal region28.9
23.98
Cnn3sAMYStriatum-like amygdalar nuclei7.7
8.73
Cnn3STRStriatum16.87
17.48
Cnn3STRdStriatum dorsal region17.92
18.2
Cnn3STRvStriatum ventral region8.49
8.07
Cnn3THThalamus36.34
39.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CNN3_HUMAN_158 14 158 171 AGQSVIGLQMGTNK PRIDE
CNN3_HUMAN_159 14 159 172 AGQSVIGLQMGTNK PRIDE
CNN3_HUMAN_17 16 17 32 NKIASKYDHQAEEDLR PRIDE
CNN3_HUMAN_19 14 19 32 IASKYDHQAEEDLR PRIDE
CNN3_HUMAN_192 20 192 211 MQTDKPFDQTTISLQMGTNK PRIDE
CNN3_HUMAN_193 20 193 212 MQTDKPFDQTTISLQMGTNK PRIDE
CNN3_HUMAN_2 32 2 33 THFNKGPSYGLSAEVKNKIASKYDHQAEEDLR PRIDE
CNN3_HUMAN_212 14 212 225 GASQAGMLAPGTRR PRIDE
CNN3_HUMAN_213 13 213 225 GASQAGMLAPGTR PRIDE
CNN3_HUMAN_233 19 233 251 LTLQPVDNSTISLQMGTNK PRIDE
CNN3_HUMAN_256 9 256 264 GMSVYGLGR PRIDE
CNN3_HUMAN_257 9 257 265 GMSVYGLGR PRIDE
CNN3_HUMAN_53 11 53 63 DGIILCELINK PRIDE
CNN3_HUMAN_53 18 53 70 DGIILCELINKLQPGSVK PRIDE
CNN3_HUMAN_6 11 6 16 GPSYGLSAEVK PRIDE
CNN3_HUMAN_72 19 72 90 VNESSLNWPQLENIGNFIK PRIDE
PAp00000864 13 173 185 CASQAGMTAYGTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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