AutismKB 2.0

Annotation Detail for LYPLAL1


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Basic Information Top
Gene Symbol:LYPLAL1 ( FLJ99730,KIAA1238 )
Gene Full Name: lysophospholipase-like 1
Band: 1q41
Quick LinksEntrez ID:127018; OMIM: NA; Uniprot ID:LYPL1_HUMAN; ENSEMBL ID: ENSG00000143353; HGNC ID: 20440
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor10 / 26384537
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia0 / 972500 
normal94 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer10 / 10268097
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood2 / 12347816
bone1 / 7165513
bone marrow2 / 4880140
brain27 / 110098924
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye7 / 21105433
heart7 / 8962678
intestine2 / 2344728
kidney16 / 21177775
larynx0 / 241450 
liver5 / 20774324
lung12 / 33697435
lymph0 / 442700 
lymph node11 / 91610120
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta3 / 28082510
prostate12 / 18934563
salivary gland1 / 2015549
skin6 / 21057428
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus1 / 8113112
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9307_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.07 ± 0.28
Basal Forebrain9.26 ± 0.14
Basal Part of Pons8.81 ± 0.2
Cerebellar Cortex9.07 ± 0.21
Cerebellar Nuclei9.07 ± 0.35
Claustrum8.77 ± 0.33
Epithalamus9.39 ± 0.15
Frontal Lobe9.14 ± 0.24
Globus Pallidus9.77 ± 0.14
Hypothalamus9.45 ± 0.17
Insula9.21 ± 0.3
Limbic Lobe9.01 ± 0.3
Mesencephalon9.17 ± 0.25
Myelencephalon9.09 ± 0.3
Occipital Lobe8.82 ± 0.26
Parietal Lobe9.05 ± 0.23
Pontine Tegmentum9.23 ± 0.24
Striatum9.16 ± 0.24
Subthalamus9.3 ± 0.18
Temporal Lobe9.09 ± 0.28
Thalamus9.08 ± 0.26
White Matter9.96 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Lyplal1CBCerebellum0.18
0.56
Lyplal1CTXCerebral cortex0.28
0.53
Lyplal1HIPHippocampal region0.25
0.25
Lyplal1HPFHippocampal formation0.18
0.17
Lyplal1HYHypothalamus0.09
0.16
Lyplal1LSXLateral septal complex0.07
0.06
Lyplal1MBMidbrain0.09
0.2
Lyplal1MYMedulla0.03
0.06
Lyplal1OLFOlfactory bulb0.92
2.32
Lyplal1PPons0.11
0.23
Lyplal1PALPallidum0.06
0.1
Lyplal1RHPRetrohippocampal region0.05
0.04
Lyplal1sAMYStriatum-like amygdalar nuclei0.04
0
Lyplal1STRStriatum0.06
0.07
Lyplal1STRdStriatum dorsal region0.07
0.09
Lyplal1STRvStriatum ventral region0.03
0.02
Lyplal1THThalamus0.22
0.34
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
LYPL1_HUMAN_1 10 1 10 AAASGSVLQR PRIDE
LYPL1_HUMAN_2 10 2 11 AAASGSVLQR PRIDE
PAp00133593 19 20 38 HSASLIFLHGSGDSGQGLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018