AutismKB 2.0

Annotation Detail for CNTFR


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Basic Information Top
Gene Symbol:CNTFR ( MGC1774 )
Gene Full Name: ciliary neurotrophic factor receptor
Band: 9p13.3
Quick LinksEntrez ID:1271; OMIM: 118946; Uniprot ID:CNTFR_HUMAN; ENSEMBL ID: ENSG00000122756; HGNC ID: 2170
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal60 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain44 / 110098939
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle3 / 10771527
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis1 / 3304423
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205723_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.45
Adipocyte4.3
AdrenalCortex4.6
Adrenalgland3.7
Amygdala6.75
Appendix4.05
AtrioventricularNode3.15
BDCA4+_DentriticCells4.85
Bonemarrow4.2
BronchialEpithelialCells4.15
CD105+_Endothelial4.35
CD14+_Monocytes4.6
CD19+_BCells(neg._sel.)4.6
CD33+_Myeloid5.55
CD34+5.15
CD4+_Tcells4.75
CD56+_NKCells5.2
CD71+_EarlyErythroid4.05
CD8+_Tcells4.25
CardiacMyocytes10.75
Caudatenucleus3.9
Cerebellum4.2
CerebellumPeduncles4.9
CiliaryGanglion2.95
CingulateCortex4.4
Colorectaladenocarcinoma5.05
DorsalRootGanglion3.2
FetalThyroid4.2
Fetalbrain4.3
Fetalliver5.7
Fetallung3.6
GlobusPallidus3.15
Heart5.6
Hypothalamus4.7
Kidney3.7
Leukemia_chronicMyelogenousK-5623.95
Leukemia_promyelocytic-HL-604
Leukemialymphoblastic(MOLT-4)3.75
Liver6.1
Lung4.75
Lymphnode3.8
Lymphoma_burkitts(Daudi)5.55
Lymphoma_burkitts(Raji)6.15
MedullaOblongata3.9
OccipitalLobe3.9
OlfactoryBulb3.25
Ovary3.6
Pancreas3.5
PancreaticIslet4.6
ParietalLobe4.55
Pituitary5.1
Placenta4.5
Pons4.1
PrefrontalCortex5.65
Prostate5.1
Salivarygland3.7
SkeletalMuscle5.1
Skin3.25
SmoothMuscle4.9
Spinalcord4.65
SubthalamicNucleus3.85
SuperiorCervicalGanglion4.9
TemporalLobe3.95
Testis4.85
TestisGermCell3.6
TestisIntersitial3.65
TestisLeydigCell4.6
TestisSeminiferousTubule3.7
Thalamus4.35
Thymus3.45
Thyroid5.45
Tongue4.3
Tonsil4.2
Trachea3.6
TrigeminalGanglion4.1
Uterus3.35
UterusCorpus3.8
WholeBlood4.8
Wholebrain3.7
colon6.35
pineal_day5.42
pineal_night5.18
retina5.3
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12819_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.74 ± 0.81
Basal Forebrain3.69 ± 0.3
Basal Part of Pons3.12 ± 0.54
Cerebellar Cortex3.69 ± 0.54
Cerebellar Nuclei3.83 ± 0.67
Claustrum3.72 ± 0.75
Epithalamus3.19 ± 0.85
Frontal Lobe3.43 ± 0.66
Globus Pallidus5.17 ± 0.66
Hypothalamus3.26 ± 0.96
Insula3.08 ± 0.7
Limbic Lobe3.44 ± 0.78
Mesencephalon3.93 ± 0.69
Myelencephalon3.61 ± 0.81
Occipital Lobe4.22 ± 0.8
Parietal Lobe3.78 ± 0.6
Pontine Tegmentum3.84 ± 0.71
Striatum4.16 ± 0.69
Subthalamus3.9 ± 0.82
Temporal Lobe3.45 ± 0.58
Thalamus3.94 ± 0.55
White Matter2.28 ± 1.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CntfrCBCerebellum100
100
CntfrCTXCerebral cortex100
98.02
CntfrHIPHippocampal region67.72
77.45
CntfrHPFHippocampal formation87.91
91.91
CntfrHYHypothalamus96.88
80.47
CntfrLSXLateral septal complex88
74.31
CntfrMBMidbrain97.52
92.1
CntfrMYMedulla99.99
100
CntfrOLFOlfactory bulb100
100
CntfrPPons98.95
100
CntfrPALPallidum96.92
88.56
CntfrRHPRetrohippocampal region100
100
CntfrsAMYStriatum-like amygdalar nuclei98.46
76.03
CntfrSTRStriatum93.83
73.1
CntfrSTRdStriatum dorsal region93.35
68.74
CntfrSTRvStriatum ventral region93.64
78.81
CntfrTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00468849 13 25 37 HSPQEAPHVQYER Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018