AutismKB 2.0

Annotation Detail for CNTN1


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Basic Information Top
Gene Symbol:CNTN1 ( F3,GP135 )
Gene Full Name: contactin 1
Band: 12q12
Quick LinksEntrez ID:1272; OMIM: 600016; Uniprot ID:CNTN1_HUMAN; ENSEMBL ID: ENSG00000018236; HGNC ID: 2171
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus31 / 56401254
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal136 / 336030740
ovarian tumor0 / 766820 
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain83 / 110098975
cervix0 / 481710 
connective tissue5 / 14925533
ear9 / 16212555
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve4 / 15768253
ovary0 / 1020510 
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211203_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.5
Adipocyte6.1
AdrenalCortex6.65
Adrenalgland5.25
Amygdala11.45
Appendix6.35
AtrioventricularNode4.95
BDCA4+_DentriticCells6.2
Bonemarrow6.25
BronchialEpithelialCells9.05
CD105+_Endothelial6.2
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.55
CD33+_Myeloid7.85
CD34+7.95
CD4+_Tcells6.55
CD56+_NKCells7.25
CD71+_EarlyErythroid5.75
CD8+_Tcells5.85
CardiacMyocytes7.95
Caudatenucleus5.6
Cerebellum14.3
CerebellumPeduncles29.05
CiliaryGanglion4.5
CingulateCortex8.75
Colorectaladenocarcinoma6.1
DorsalRootGanglion4.95
FetalThyroid5.95
Fetalbrain28.95
Fetalliver5.4
Fetallung5.05
GlobusPallidus5.6
Heart8.2
Hypothalamus8.3
Kidney5.1
Leukemia_chronicMyelogenousK-5625.55
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)4.9
Liver8.25
Lung6.7
Lymphnode5.3
Lymphoma_burkitts(Daudi)7.95
Lymphoma_burkitts(Raji)8.65
MedullaOblongata6.85
OccipitalLobe13.5
OlfactoryBulb5
Ovary4.15
Pancreas4.95
PancreaticIslet21.85
ParietalLobe8.55
Pituitary7.35
Placenta6.35
Pons6.95
PrefrontalCortex15.8
Prostate7.15
Salivarygland5.3
SkeletalMuscle7.7
Skin4.9
SmoothMuscle6.9
Spinalcord7.2
SubthalamicNucleus10.2
SuperiorCervicalGanglion11.3
TemporalLobe6.5
Testis5.25
TestisGermCell5.1
TestisIntersitial5.7
TestisLeydigCell6.15
TestisSeminiferousTubule5.25
Thalamus8.55
Thymus4.8
Thyroid7.55
Tongue6.15
Tonsil5.95
Trachea5.15
TrigeminalGanglion6.3
Uterus5
UterusCorpus5.65
WholeBlood6.65
Wholebrain5.1
colon6.05
pineal_day57.14
pineal_night54.08
retina7.425
small_intestine5.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11199_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.39 ± 0.21
Basal Forebrain8.78 ± 0.25
Basal Part of Pons9.18 ± 0.2
Cerebellar Cortex9.61 ± 0.12
Cerebellar Nuclei8.84 ± 0.28
Claustrum9.51 ± 0.24
Epithalamus9.2 ± 0.22
Frontal Lobe9.36 ± 0.33
Globus Pallidus8.99 ± 0.2
Hypothalamus9.11 ± 0.34
Insula9.47 ± 0.17
Limbic Lobe9.6 ± 0.27
Mesencephalon9.28 ± 0.55
Myelencephalon9.26 ± 0.42
Occipital Lobe9.08 ± 0.35
Parietal Lobe9.26 ± 0.3
Pontine Tegmentum9.2 ± 0.37
Striatum8.43 ± 0.3
Subthalamus9.09 ± 0.09
Temporal Lobe9.44 ± 0.23
Thalamus9.18 ± 0.28
White Matter8.02 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cntn1CBCerebellum14.83
16.84
Cntn1CTXCerebral cortex41.04
37.45
Cntn1HIPHippocampal region71.45
77.39
Cntn1HPFHippocampal formation73.12
74.85
Cntn1HYHypothalamus31.22
27.46
Cntn1LSXLateral septal complex6.97
7.07
Cntn1MBMidbrain19.77
21.3
Cntn1MYMedulla28.79
36.09
Cntn1OLFOlfactory bulb82.29
64.8
Cntn1PPons29.33
35.16
Cntn1PALPallidum32.76
40.72
Cntn1RHPRetrohippocampal region76.1
70.62
Cntn1sAMYStriatum-like amygdalar nuclei36.02
28.6
Cntn1STRStriatum14.87
14.65
Cntn1STRdStriatum dorsal region9.73
11.05
Cntn1STRvStriatum ventral region23.44
20.55
Cntn1THThalamus39.28
39.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00068613 19 142 160 GMVLLCDPPYHFPDDLSYR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018