AutismKB 2.0

Annotation Detail for IQGAP3


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Basic Information Top
Gene Symbol:IQGAP3 ( MGC10170,MGC10831,MGC1947 )
Gene Full Name: IQ motif containing GTPase activating protein 3
Band: 1q22
Quick LinksEntrez ID:128239; OMIM: NA; Uniprot ID:IQGA3_HUMAN; ENSEMBL ID: ENSG00000183856; HGNC ID: 20669
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma2 / 10688318
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor14 / 103127135
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal22 / 33603076
ovarian tumor26 / 76682339
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow8 / 48801163
brain3 / 11009892
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine11 / 23447246
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung15 / 33697444
lymph0 / 442700 
lymph node4 / 9161043
mammary gland6 / 15327139
mouth2 / 6705229
muscle0 / 1077150 
nerve0 / 157680 
ovary26 / 102051254
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach4 / 9661941
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P329335
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.94 ± 0.59
Basal Forebrain5.6 ± 0.17
Basal Part of Pons5.69 ± 0.18
Cerebellar Cortex5.49 ± 0.45
Cerebellar Nuclei5.87 ± 0.35
Claustrum6.14 ± 0.6
Epithalamus5.16 ± 0.37
Frontal Lobe5.57 ± 0.45
Globus Pallidus5.95 ± 0.55
Hypothalamus5.55 ± 0.44
Insula5.46 ± 0.31
Limbic Lobe5.76 ± 0.49
Mesencephalon5.75 ± 0.42
Myelencephalon5.68 ± 0.51
Occipital Lobe5.69 ± 0.55
Parietal Lobe5.63 ± 0.5
Pontine Tegmentum5.49 ± 0.57
Striatum5.89 ± 0.44
Subthalamus5.83 ± 0.32
Temporal Lobe5.56 ± 0.49
Thalamus5.61 ± 0.48
White Matter5.75 ± 0.4
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
IQGA3_HUMAN_0 0 0 0 FLLAITSSVDQIPYGMR PRIDE
IQGA3_HUMAN_0 0 0 0 LIFQMPQNK PRIDE
IQGA3_HUMAN_0 0 0 0 TALQEEIK PRIDE
IQGA3_HUMAN_0 0 0 0 VNVNLLIFLLNKK PRIDE
IQGA3_HUMAN_371 13 371 383 GDQEQAMLHAVQR PRIDE
IQGA3_HUMAN_972 9 972 980 LIFQMPQNK PRIDE
IQGA3_HUMAN_973 9 973 981 LIFQMPQNK PRIDE
PAp00069192 17 1207 1223 HALGAVAQLLQHAAAGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018