AutismKB 2.0

Annotation Detail for ARHGEF19


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Basic Information Top
Gene Symbol:ARHGEF19 ( FLJ33962,RP4-733M16.1,WGEF )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 19
Band: 1p36.13
Quick LinksEntrez ID:128272; OMIM: 612496; Uniprot ID:ARHGJ_HUMAN; ENSEMBL ID: ENSG00000142632; HGNC ID: 26604
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst5 / 6231980
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor8 / 26384530
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal36 / 336030710
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites4 / 4001599
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain6 / 11009895
cervix4 / 4817183
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye6 / 21105428
heart4 / 8962644
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle0 / 1077150 
nerve1 / 1576863
ovary8 / 10205178
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta2 / 2808257
prostate11 / 18934558
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9365_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.29 ± 0.99
Basal Forebrain1.68 ± 0.25
Basal Part of Pons1.35 ± 0.34
Cerebellar Cortex1.65 ± 0.75
Cerebellar Nuclei2.09 ± 0.81
Claustrum2.68 ± 0.76
Epithalamus1.55 ± 0.69
Frontal Lobe1.62 ± 0.65
Globus Pallidus2.15 ± 0.33
Hypothalamus1.76 ± 0.62
Insula1.48 ± 0.4
Limbic Lobe1.78 ± 0.69
Mesencephalon1.9 ± 0.65
Myelencephalon1.82 ± 0.64
Occipital Lobe1.74 ± 0.65
Parietal Lobe1.74 ± 0.76
Pontine Tegmentum1.83 ± 0.7
Striatum2.08 ± 0.66
Subthalamus1.91 ± 0.7
Temporal Lobe1.68 ± 0.68
Thalamus1.75 ± 0.64
White Matter2.11 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Arhgef19CBCerebellum8.16
11.22
Arhgef19CTXCerebral cortex1.75
1.41
Arhgef19HIPHippocampal region1.52
1.45
Arhgef19HPFHippocampal formation2.53
2.44
Arhgef19HYHypothalamus0.84
0.73
Arhgef19LSXLateral septal complex0.54
0.39
Arhgef19MBMidbrain0.76
1.3
Arhgef19MYMedulla2.66
3.35
Arhgef19OLFOlfactory bulb1.54
2.15
Arhgef19PPons2.71
4.33
Arhgef19PALPallidum0.69
0.68
Arhgef19RHPRetrohippocampal region4.34
3.99
Arhgef19sAMYStriatum-like amygdalar nuclei0.55
0.52
Arhgef19STRStriatum1.06
0.87
Arhgef19STRdStriatum dorsal region1.41
0.99
Arhgef19STRvStriatum ventral region0.65
0.82
Arhgef19THThalamus0.95
0.9
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018