AutismKB 2.0

Annotation Detail for C22orf25


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:C22orf25 ( DKFZp761P1121 )
Gene Full Name: chromosome 22 open reading frame 25
Band: 22q11.21
Quick LinksEntrez ID:128989; OMIM: NA; Uniprot ID:CV025_HUMAN; ENSEMBL ID: ENSG00000183597; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus21 / 56401237
neonate6 / 31097192
infant0 / 236200 
juvenile2 / 5555635
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma4 / 10688337
head and neck tumor10 / 13630273
kidney tumor2 / 6895929
leukemia7 / 9584273
liver tumor3 / 9635931
lung tumor7 / 10312767
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal150 / 336030744
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood20 / 123478161
bone2 / 7165527
bone marrow6 / 48801122
brain51 / 110098946
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye2 / 2110549
heart5 / 8962655
intestine3 / 23447212
kidney10 / 21177747
larynx0 / 241450 
liver3 / 20774314
lung12 / 33697435
lymph2 / 4427045
lymph node1 / 9161010
mammary gland6 / 15327139
mouth4 / 6705259
muscle2 / 10771518
nerve2 / 15768126
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta17 / 28082560
prostate6 / 18934531
salivary gland0 / 201550 
skin14 / 21057466
spleen5 / 5395292
stomach1 / 9661910
testis11 / 33044233
thymus4 / 8113149
thyroid8 / 47473168
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord1 / 1368073
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5860_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.05 ± 0.4
Basal Forebrain6.64 ± 0.68
Basal Part of Pons6.49 ± 0.44
Cerebellar Cortex6.25 ± 0.34
Cerebellar Nuclei7.07 ± 0.4
Claustrum7.18 ± 0.75
Epithalamus6 ± 0.59
Frontal Lobe6.69 ± 0.59
Globus Pallidus7.61 ± 0.32
Hypothalamus6.57 ± 0.36
Insula6.52 ± 0.43
Limbic Lobe7.07 ± 0.66
Mesencephalon7.11 ± 0.65
Myelencephalon6.85 ± 0.55
Occipital Lobe7.28 ± 0.58
Parietal Lobe6.97 ± 0.58
Pontine Tegmentum6.83 ± 0.41
Striatum6.65 ± 0.66
Subthalamus6.86 ± 0.47
Temporal Lobe6.73 ± 0.51
Thalamus6.92 ± 0.42
White Matter7.48 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
D16H22S680ECBCerebellum15.93
22.52
D16H22S680ECTXCerebral cortex98.8
95.11
D16H22S680EHIPHippocampal region70.82
83.96
D16H22S680EHPFHippocampal formation75.8
83.72
D16H22S680EHYHypothalamus70.67
71.7
D16H22S680ELSXLateral septal complex77.36
63.08
D16H22S680EMBMidbrain69.19
82.13
D16H22S680EMYMedulla68.38
100
D16H22S680EOLFOlfactory bulb81.5
89.2
D16H22S680EPPons64.5
94.02
D16H22S680EPALPallidum70.43
82.21
D16H22S680ERHPRetrohippocampal region81.59
82.91
D16H22S680EsAMYStriatum-like amygdalar nuclei68.44
65.96
D16H22S680ESTRStriatum46.1
39.17
D16H22S680ESTRdStriatum dorsal region39.43
32.91
D16H22S680ESTRvStriatum ventral region46.22
38.44
D16H22S680ETHThalamus75.89
76.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00159311 16 20 35 LILAANRDEFYSRPSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018