AutismKB 2.0

Annotation Detail for ZNF280A


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Basic Information Top
Gene Symbol:ZNF280A ( 3'OY11.1,SUHW1,ZNF280,ZNF636 )
Gene Full Name: zinc finger protein 280A
Band: 22q11.22
Quick LinksEntrez ID:129025; OMIM: NA; Uniprot ID:Z280A_HUMAN; ENSEMBL ID: ENSG00000169548; HGNC ID: 18597
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal3 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216034_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.3
Adipocyte4.4
AdrenalCortex4.85
Adrenalgland3.85
Amygdala4.6
Appendix5.45
AtrioventricularNode4.6
BDCA4+_DentriticCells4.6
Bonemarrow4.55
BronchialEpithelialCells4.35
CD105+_Endothelial4.35
CD14+_Monocytes4.65
CD19+_BCells(neg._sel.)4.65
CD33+_Myeloid5.6
CD34+5.45
CD4+_Tcells4.6
CD56+_NKCells5.1
CD71+_EarlyErythroid4.15
CD8+_Tcells4.1
CardiacMyocytes5.9
Caudatenucleus4
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.65
CingulateCortex4.7
Colorectaladenocarcinoma4.45
DorsalRootGanglion4.15
FetalThyroid4.4
Fetalbrain4.75
Fetalliver3.9
Fetallung3.55
GlobusPallidus3.45
Heart6
Hypothalamus4.8
Kidney3.75
Leukemia_chronicMyelogenousK-56218.25
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.55
Liver5.85
Lung4.85
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.8
Lymphoma_burkitts(Raji)6.45
MedullaOblongata4.5
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary3.3
Pancreas3.65
PancreaticIslet4.8
ParietalLobe4.85
Pituitary5.35
Placenta4.5
Pons4.35
PrefrontalCortex5.5
Prostate5.15
Salivarygland3.65
SkeletalMuscle5.8
Skin3.75
SmoothMuscle5
Spinalcord4.75
SubthalamicNucleus4.45
SuperiorCervicalGanglion12.2
TemporalLobe4.1
Testis3.8
TestisGermCell3.65
TestisIntersitial3.8
TestisLeydigCell4.45
TestisSeminiferousTubule3.85
Thalamus4.65
Thymus3.45
Thyroid5.55
Tongue6.15
Tonsil4.35
Trachea3.75
TrigeminalGanglion6.05
Uterus3.65
UterusCorpus4.4
WholeBlood4.8
Wholebrain3.75
colon4.45
pineal_day5.48
pineal_night5.34
retina5.425
small_intestine4.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_823_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.05 ± 1
Basal Forebrain1.54 ± 0.21
Basal Part of Pons1.23 ± 0.32
Cerebellar Cortex1.42 ± 0.75
Cerebellar Nuclei1.79 ± 0.68
Claustrum2.47 ± 0.91
Epithalamus1.39 ± 0.88
Frontal Lobe1.41 ± 0.67
Globus Pallidus2.2 ± 0.32
Hypothalamus1.67 ± 0.74
Insula1.42 ± 0.49
Limbic Lobe1.55 ± 0.62
Mesencephalon1.69 ± 0.64
Myelencephalon1.59 ± 0.63
Occipital Lobe1.62 ± 0.59
Parietal Lobe1.57 ± 0.68
Pontine Tegmentum1.64 ± 0.74
Striatum1.69 ± 0.49
Subthalamus1.7 ± 0.6
Temporal Lobe1.48 ± 0.66
Thalamus1.57 ± 0.58
White Matter2.13 ± 0.39
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
Z280A_HUMAN_524 8 524 531 KKTAMNTR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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