Annotation Detail for DIS3L2
Basic Information Top
| Gene Symbol: | DIS3L2 ( FAM6A,FLJ36974,MGC42174 ) |
|---|---|
| Gene Full Name: | DIS3 mitotic control homolog (S. cerevisiae)-like 2 |
| Band: | 2q37.1 |
| Quick Links | Entrez ID:129563; OMIM: NA; Uniprot ID:DI3L2_HUMAN; ENSEMBL ID: ENSG00000144535; HGNC ID: 28648 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.471637
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 7 / 564012 | 12 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 64 / 1939121 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 78 / 3360307 | 23 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 6 / 125680 | 47 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 10 / 125191 | 79 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 1 / 123478 | 8 |  |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 18 / 1100989 | 16 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 0 / 89626 | 0 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 9 / 336974 | 26 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 13 / 67052 | 193 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 2 / 15768 | 126 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 5 / 96619 | 51 | |
| testis | 10 / 330442 | 30 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P113888
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.02 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.07 ± 0.39 | |
| Basal Part of Pons | 4.5 ± 0.42 | |
| Cerebellar Cortex | 4.17 ± 0.56 | |
| Cerebellar Nuclei | 4.03 ± 0.59 | |
| Claustrum | 3.69 ± 0.76 | |
| Epithalamus | 4.37 ± 0.38 | |
| Frontal Lobe | 4.24 ± 0.54 | |
| Globus Pallidus | 3.81 ± 0.5 | |
| Hypothalamus | 4.01 ± 0.36 | |
| Insula | 4.31 ± 0.46 | |
| Limbic Lobe | 4.26 ± 0.54 | |
| Mesencephalon | 4.11 ± 0.45 | |
| Myelencephalon | 4.21 ± 0.45 | |
| Occipital Lobe | 4.38 ± 0.39 | |
| Parietal Lobe | 4.22 ± 0.54 | |
| Pontine Tegmentum | 4.04 ± 0.61 | |
| Striatum | 4.12 ± 0.51 | |
| Subthalamus | 4.05 ± 0.67 | |
| Temporal Lobe | 4.26 ± 0.45 | |
| Thalamus | 4.3 ± 0.57 | |
| White Matter | 5.13 ± 0.32 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| 4930429A22Rik | CB | Cerebellum | 20.3 | |
| 31.69 | | |||
| 4930429A22Rik | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| 4930429A22Rik | HIP | Hippocampal region | 68.22 | |
| 100 | | |||
| 4930429A22Rik | HPF | Hippocampal formation | 77.91 | |
| 100 | | |||
| 4930429A22Rik | HY | Hypothalamus | 54.44 | |
| 48.79 | | |||
| 4930429A22Rik | LSX | Lateral septal complex | 80.87 | |
| 59.3 | | |||
| 4930429A22Rik | MB | Midbrain | 43.53 | |
| 43.37 | | |||
| 4930429A22Rik | MY | Medulla | 26.62 | |
| 36.91 | | |||
| 4930429A22Rik | OLF | Olfactory bulb | 74.65 | |
| 68.69 | | |||
| 4930429A22Rik | P | Pons | 31.14 | |
| 39.12 | | |||
| 4930429A22Rik | PAL | Pallidum | 51.02 | |
| 47.61 | | |||
| 4930429A22Rik | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| 4930429A22Rik | sAMY | Striatum-like amygdalar nuclei | 40.39 | |
| 30.59 | | |||
| 4930429A22Rik | STR | Striatum | 52.44 | |
| 37.94 | | |||
| 4930429A22Rik | STRd | Striatum dorsal region | 51.23 | |
| 37.58 | | |||
| 4930429A22Rik | STRv | Striatum ventral region | 47.77 | |
| 31.8 | | |||
| 4930429A22Rik | TH | Thalamus | 78.14 | |
| 68.68 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00074181 | 16 | 492 | 507 | LSYEHAQSMIESPTEK | Peptide Atlas |