AutismKB 2.0

Annotation Detail for UBR3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:UBR3 ( DKFZp434P117,DKFZp686N10185,FLJ37422,KIAA2024,MGC126489,ZNF650 )
Gene Full Name: ubiquitin protein ligase E3 component n-recognin 3 (putative)
Band: 2q31.1
Quick LinksEntrez ID:130507; OMIM: NA; Uniprot ID:UBR3_HUMAN; ENSEMBL ID: ENSG00000144357; HGNC ID: 30467
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia7 / 9725071
normal127 / 336030737
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone2 / 7165527
bone marrow1 / 4880120
brain58 / 110098952
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney9 / 21177742
larynx0 / 241450 
liver7 / 20774333
lung8 / 33697423
lymph0 / 442700 
lymph node8 / 9161087
mammary gland3 / 15327119
mouth2 / 6705229
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas1 / 2148124
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate7 / 18934536
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach0 / 966190 
testis7 / 33044221
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea9 / 52413171
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P5405
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.88 ± 0.51
Basal Forebrain7.09 ± 0.13
Basal Part of Pons7.12 ± 0.31
Cerebellar Cortex7.12 ± 0.2
Cerebellar Nuclei7.05 ± 0.35
Claustrum7.16 ± 0.49
Epithalamus6.42 ± 0.3
Frontal Lobe7.26 ± 0.29
Globus Pallidus6.37 ± 0.17
Hypothalamus7.04 ± 0.21
Insula7.25 ± 0.24
Limbic Lobe7.22 ± 0.38
Mesencephalon7.14 ± 0.32
Myelencephalon7.04 ± 0.35
Occipital Lobe6.92 ± 0.36
Parietal Lobe7.15 ± 0.32
Pontine Tegmentum7.04 ± 0.39
Striatum6.75 ± 0.39
Subthalamus7.28 ± 0.37
Temporal Lobe7.22 ± 0.27
Thalamus7.01 ± 0.31
White Matter7.06 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1110059H15RikCBCerebellum44.52
80.64
1110059H15RikCTXCerebral cortex100
100
1110059H15RikHIPHippocampal region97.48
100
1110059H15RikHPFHippocampal formation100
100
1110059H15RikHYHypothalamus82.7
73.59
1110059H15RikLSXLateral septal complex100
100
1110059H15RikMBMidbrain87.13
91.57
1110059H15RikMYMedulla83.74
100
1110059H15RikOLFOlfactory bulb100
100
1110059H15RikPPons74.96
92.9
1110059H15RikPALPallidum82.96
87.72
1110059H15RikRHPRetrohippocampal region100
100
1110059H15RiksAMYStriatum-like amygdalar nuclei100
100
1110059H15RikSTRStriatum100
100
1110059H15RikSTRdStriatum dorsal region100
100
1110059H15RikSTRvStriatum ventral region100
100
1110059H15RikTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00074472 12 1497 1508 LYSIDSEYNPWR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved