AutismKB 2.0

Annotation Detail for ADH7


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Basic Information Top
Gene Symbol:ADH7 ( ADH4 )
Gene Full Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Band: 4q23
Quick LinksEntrez ID:131; OMIM: 600086; Uniprot ID:ADH7_HUMAN; ENSEMBL ID: ENSG00000196344; HGNC ID: 256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor28 / 172901619
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal19 / 33603075
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus28 / 202091385
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung14 / 33697441
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth9 / 67052134
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach1 / 9661910
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea16 / 52413305
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210505_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.2
Adipocyte7.25
AdrenalCortex9.25
Adrenalgland6.8
Amygdala8
Appendix10.2
AtrioventricularNode7.85
BDCA4+_DentriticCells7.8
Bonemarrow8.35
BronchialEpithelialCells7.25
CD105+_Endothelial7.8
CD14+_Monocytes8.35
CD19+_BCells(neg._sel.)8.15
CD33+_Myeloid9.9
CD34+9.45
CD4+_Tcells7.9
CD56+_NKCells8.3
CD71+_EarlyErythroid10.8
CD8+_Tcells7
CardiacMyocytes14.85
Caudatenucleus6.95
Cerebellum8
CerebellumPeduncles9.3
CiliaryGanglion6.4
CingulateCortex8.25
Colorectaladenocarcinoma7.85
DorsalRootGanglion8.8
FetalThyroid7.65
Fetalbrain7.4
Fetalliver6.9
Fetallung5.7
GlobusPallidus7.15
Heart13.75
Hypothalamus8
Kidney7.3
Leukemia_chronicMyelogenousK-5626.9
Leukemia_promyelocytic-HL-606.8
Leukemialymphoblastic(MOLT-4)6.1
Liver11.9
Lung8.5
Lymphnode6.25
Lymphoma_burkitts(Daudi)10.15
Lymphoma_burkitts(Raji)12.4
MedullaOblongata6.85
OccipitalLobe6.95
OlfactoryBulb5.95
Ovary5.8
Pancreas6.5
PancreaticIslet8.55
ParietalLobe8.65
Pituitary8.9
Placenta7.8
Pons7.55
PrefrontalCortex9.2
Prostate9.1
Salivarygland6.4
SkeletalMuscle11.7
Skin8.05
SmoothMuscle8.65
Spinalcord8.35
SubthalamicNucleus7.4
SuperiorCervicalGanglion12.55
TemporalLobe7.3
Testis6.6
TestisGermCell6.05
TestisIntersitial6.7
TestisLeydigCell8
TestisSeminiferousTubule6.65
Thalamus8.15
Thymus5.8
Thyroid9.5
Tongue100.7
Tonsil9.7
Trachea23.25
TrigeminalGanglion9.45
Uterus6.2
UterusCorpus7.55
WholeBlood8.4
Wholebrain5.85
colon8
pineal_day9.36
pineal_night9.5
retina9.625
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P92562
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.48 ± 1.05
Basal Forebrain2.01 ± 0.2
Basal Part of Pons1.63 ± 0.33
Cerebellar Cortex1.84 ± 0.77
Cerebellar Nuclei2.22 ± 0.69
Claustrum2.91 ± 0.89
Epithalamus1.64 ± 0.69
Frontal Lobe1.83 ± 0.72
Globus Pallidus2.54 ± 0.3
Hypothalamus2.26 ± 1.09
Insula1.84 ± 0.43
Limbic Lobe1.96 ± 0.61
Mesencephalon2.08 ± 0.67
Myelencephalon1.99 ± 0.66
Occipital Lobe1.96 ± 0.56
Parietal Lobe2.03 ± 0.84
Pontine Tegmentum2.01 ± 0.68
Striatum2.14 ± 0.51
Subthalamus2.06 ± 0.64
Temporal Lobe1.81 ± 0.53
Thalamus1.93 ± 0.58
White Matter2.53 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Adh7CBCerebellum5.03
6.15
Adh7CTXCerebral cortex6.29
4.66
Adh7HIPHippocampal region4.73
4.42
Adh7HPFHippocampal formation7.11
6.1
Adh7HYHypothalamus13.1
14.74
Adh7LSXLateral septal complex0.04
0
Adh7MBMidbrain2.96
3.8
Adh7MYMedulla10.46
13.09
Adh7OLFOlfactory bulb33.52
25.39
Adh7PPons13.62
20.06
Adh7PALPallidum7
6.28
Adh7RHPRetrohippocampal region12.58
9.59
Adh7sAMYStriatum-like amygdalar nuclei5.21
3.48
Adh7STRStriatum4.72
3.64
Adh7STRdStriatum dorsal region1.64
1.34
Adh7STRvStriatum ventral region17.03
12.13
Adh7THThalamus3.58
2.66
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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