AutismKB 2.0

Annotation Detail for CPNE4


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Basic Information Top
Gene Symbol:CPNE4 ( COPN4,CPN4,MGC15604 )
Gene Full Name: copine IV
Band: 3q22.1
Quick LinksEntrez ID:131034; OMIM: 604208; Uniprot ID:CPNE4_HUMAN; ENSEMBL ID: ENSG00000196353; HGNC ID: 2317
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult33 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor0 / 1363020 
kidney tumor7 / 68959101
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal145 / 336030743
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer10 / 10268097
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain89 / 110098980
cervix0 / 481710 
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart5 / 8962655
intestine0 / 2344720 
kidney8 / 21177737
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate21 / 189345110
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis3 / 3304429
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.85 ± 0.93
Basal Forebrain4.84 ± 0.34
Basal Part of Pons4.63 ± 0.35
Cerebellar Cortex4.54 ± 0.63
Cerebellar Nuclei3.89 ± 0.86
Claustrum7.33 ± 0.62
Epithalamus4.39 ± 0.8
Frontal Lobe5.63 ± 0.84
Globus Pallidus3.96 ± 1.35
Hypothalamus4.66 ± 0.7
Insula6.2 ± 0.74
Limbic Lobe6.05 ± 0.93
Mesencephalon5 ± 0.99
Myelencephalon5.42 ± 0.83
Occipital Lobe5.92 ± 0.63
Parietal Lobe5.46 ± 0.71
Pontine Tegmentum5.45 ± 0.81
Striatum4.61 ± 1.51
Subthalamus5.3 ± 0.83
Temporal Lobe5.86 ± 0.61
Thalamus5.95 ± 0.68
White Matter3.32 ± 0.56
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cpne4CBCerebellum1.75
2.25
Cpne4CTXCerebral cortex25.8
26.41
Cpne4HIPHippocampal region42.86
73.28
Cpne4HPFHippocampal formation30.74
46.48
Cpne4HYHypothalamus2.46
2.59
Cpne4LSXLateral septal complex32.68
38.48
Cpne4MBMidbrain7.1
7.47
Cpne4MYMedulla10.5
14.27
Cpne4OLFOlfactory bulb53.96
66.23
Cpne4PPons3.55
4.59
Cpne4PALPallidum7.32
8.33
Cpne4RHPRetrohippocampal region12.73
13.51
Cpne4sAMYStriatum-like amygdalar nuclei17.81
18.23
Cpne4STRStriatum10.35
13.5
Cpne4STRdStriatum dorsal region6.54
10.53
Cpne4STRvStriatum ventral region10.22
11.94
Cpne4THThalamus18.67
22.94
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CPNE4_HUMAN_500 9 500 508 DIVQFVPFR PRIDE
PAp00412132 9 501 509 DIVQFVPFR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018