AutismKB 2.0

Annotation Detail for TMEM42


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Basic Information Top
Gene Symbol:TMEM42 ( MGC29956 )
Gene Full Name: transmembrane protein 42
Band: 3p21.31
Quick LinksEntrez ID:131616; OMIM: NA; Uniprot ID:TMM42_HUMAN; ENSEMBL ID: ENSG00000169964; HGNC ID: 28444
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma4 / 8282348
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal65 / 336030719
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone3 / 7165541
bone marrow0 / 488010 
brain14 / 110098912
cervix1 / 4817120
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine3 / 23447212
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung11 / 33697432
lymph0 / 442700 
lymph node4 / 9161043
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta1 / 2808253
prostate2 / 18934510
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1295_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.89 ± 0.62
Basal Forebrain5.1 ± 0.66
Basal Part of Pons5.2 ± 0.3
Cerebellar Cortex4.85 ± 0.47
Cerebellar Nuclei5.01 ± 0.41
Claustrum4.4 ± 0.85
Epithalamus5.48 ± 0.54
Frontal Lobe5.12 ± 0.48
Globus Pallidus5.35 ± 0.73
Hypothalamus5.28 ± 0.67
Insula5.13 ± 0.47
Limbic Lobe4.7 ± 0.58
Mesencephalon4.87 ± 0.5
Myelencephalon4.93 ± 0.6
Occipital Lobe4.31 ± 0.48
Parietal Lobe4.81 ± 0.52
Pontine Tegmentum4.93 ± 0.61
Striatum4.82 ± 0.5
Subthalamus5.1 ± 0.63
Temporal Lobe5.14 ± 0.5
Thalamus4.86 ± 0.52
White Matter5.98 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem42CBCerebellum18.81
23.15
Tmem42CTXCerebral cortex30.22
21.95
Tmem42HIPHippocampal region10
10.21
Tmem42HPFHippocampal formation10.3
9.42
Tmem42HYHypothalamus1.09
1.25
Tmem42LSXLateral septal complex0.46
0.41
Tmem42MBMidbrain3.36
3.23
Tmem42MYMedulla8.37
8.89
Tmem42OLFOlfactory bulb22.21
16.64
Tmem42PPons2.54
2.77
Tmem42PALPallidum4.55
3.85
Tmem42RHPRetrohippocampal region10.86
8.39
Tmem42sAMYStriatum-like amygdalar nuclei2.26
1.62
Tmem42STRStriatum3.49
2.43
Tmem42STRdStriatum dorsal region3.27
2.32
Tmem42STRvStriatum ventral region5.88
3.71
Tmem42THThalamus2.3
1.91
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018