AutismKB 2.0

Annotation Detail for CORT


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Basic Information Top
Gene Symbol:CORT ( CST-14,CST-17,CST-29 )
Gene Full Name: cortistatin
Band: 1p36.22
Quick LinksEntrez ID:1325; OMIM: 602784; Uniprot ID:CORT_HUMAN; ENSEMBL ID: ENSG00000175279; HGNC ID: 2257
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus24 / 56401242
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma8 / 10688374
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal91 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain22 / 110098919
cervix5 / 48171103
connective tissue11 / 14925573
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye11 / 21105452
heart2 / 8962622
intestine5 / 23447221
kidney11 / 21177751
larynx0 / 241450 
liver0 / 2077430 
lung14 / 33697441
lymph0 / 442700 
lymph node4 / 9161043
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta7 / 28082524
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210182_at
Cell line Expression level Expression bar
721_B_lymphoblasts80.9
Adipocyte55.75
AdrenalCortex77.6
Adrenalgland67.85
Amygdala75.25
Appendix79.15
AtrioventricularNode110.9
BDCA4+_DentriticCells40.2
Bonemarrow96.2
BronchialEpithelialCells63.1
CD105+_Endothelial58.9
CD14+_Monocytes44.9
CD19+_BCells(neg._sel.)46.4
CD33+_Myeloid58.55
CD34+50.9
CD4+_Tcells70.9
CD56+_NKCells40.05
CD71+_EarlyErythroid68.8
CD8+_Tcells56.9
CardiacMyocytes107.05
Caudatenucleus68.8
Cerebellum57.3
CerebellumPeduncles94.15
CiliaryGanglion89.8
CingulateCortex157.3
Colorectaladenocarcinoma80.05
DorsalRootGanglion103.6
FetalThyroid68.1
Fetalbrain77.65
Fetalliver58.9
Fetallung46.35
GlobusPallidus64.6
Heart132.1
Hypothalamus73.6
Kidney62.45
Leukemia_chronicMyelogenousK-56262.95
Leukemia_promyelocytic-HL-6061.35
Leukemialymphoblastic(MOLT-4)48.5
Liver88.15
Lung62.3
Lymphnode64.25
Lymphoma_burkitts(Daudi)111.7
Lymphoma_burkitts(Raji)120.65
MedullaOblongata129.05
OccipitalLobe55.95
OlfactoryBulb52.25
Ovary39.9
Pancreas57.8
PancreaticIslet68.15
ParietalLobe84.85
Pituitary82.2
Placenta59.45
Pons74.05
PrefrontalCortex77.1
Prostate75.85
Salivarygland86.15
SkeletalMuscle152.55
Skin79.65
SmoothMuscle75.3
Spinalcord91.8
SubthalamicNucleus76.7
SuperiorCervicalGanglion119.45
TemporalLobe82.95
Testis87.75
TestisGermCell75.25
TestisIntersitial66.35
TestisLeydigCell91.45
TestisSeminiferousTubule88.15
Thalamus70.75
Thymus53.65
Thyroid84
Tongue69.55
Tonsil89.4
Trachea57.35
TrigeminalGanglion107.65
Uterus46.1
UterusCorpus95.45
WholeBlood62.5
Wholebrain76.7
colon49.3
pineal_day113.62
pineal_night97.1
retina80.275
small_intestine43.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_203_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.39 ± 0.78
Basal Forebrain5.55 ± 0.42
Basal Part of Pons6.35 ± 0.73
Cerebellar Cortex4.41 ± 0.43
Cerebellar Nuclei5.23 ± 0.83
Claustrum5.36 ± 0.64
Epithalamus4.16 ± 0.9
Frontal Lobe5.41 ± 0.63
Globus Pallidus4.26 ± 1.29
Hypothalamus4.34 ± 0.84
Insula5.23 ± 0.71
Limbic Lobe5.75 ± 0.63
Mesencephalon5.06 ± 0.93
Myelencephalon5.24 ± 0.83
Occipital Lobe4.6 ± 0.76
Parietal Lobe5.27 ± 0.7
Pontine Tegmentum5.41 ± 0.86
Striatum6.87 ± 0.49
Subthalamus4.47 ± 0.8
Temporal Lobe5.45 ± 0.53
Thalamus4.74 ± 0.76
White Matter3.16 ± 1.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CortCBCerebellum5.14
5.68
CortCTXCerebral cortex13.8
13.52
CortHIPHippocampal region9.57
13.73
CortHPFHippocampal formation10.52
13
CortHYHypothalamus0.89
0.65
CortLSXLateral septal complex2.74
2.56
CortMBMidbrain4.01
3.46
CortMYMedulla2.63
2.59
CortOLFOlfactory bulb8.49
7.16
CortPPons2.9
2.86
CortPALPallidum1.35
1.07
CortRHPRetrohippocampal region11.54
11.36
CortsAMYStriatum-like amygdalar nuclei1.08
1.09
CortSTRStriatum1.24
1.52
CortSTRdStriatum dorsal region1.04
1.54
CortSTRvStriatum ventral region1.29
1.2
CortTHThalamus3.28
2.54
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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