AutismKB 2.0

Annotation Detail for LIN54


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Basic Information Top
Gene Symbol:LIN54 ( CXCDC1,DKFZp686L1814,JC8.6,MGC129905,MIP120 )
Gene Full Name: lin-54 homolog (C. elegans)
Band: 4q21.22
Quick LinksEntrez ID:132660; OMIM: 613367; Uniprot ID:LIN54_HUMAN; ENSEMBL ID: ENSG00000189308; HGNC ID: 25397
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant2 / 2362084
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain13 / 110098911
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney4 / 21177718
larynx0 / 241450 
liver2 / 2077439
lung2 / 3369745
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta2 / 2808257
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis8 / 33044224
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P58382
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.67 ± 0.38
Basal Forebrain5.86 ± 0.09
Basal Part of Pons5.66 ± 0.29
Cerebellar Cortex5.81 ± 0.29
Cerebellar Nuclei5.6 ± 0.36
Claustrum5.72 ± 0.69
Epithalamus5.68 ± 0.38
Frontal Lobe5.72 ± 0.32
Globus Pallidus5.91 ± 0.22
Hypothalamus5.45 ± 0.35
Insula5.74 ± 0.21
Limbic Lobe5.87 ± 0.34
Mesencephalon5.79 ± 0.38
Myelencephalon5.73 ± 0.41
Occipital Lobe5.83 ± 0.34
Parietal Lobe5.86 ± 0.39
Pontine Tegmentum5.85 ± 0.36
Striatum5.73 ± 0.26
Subthalamus5.68 ± 0.4
Temporal Lobe5.82 ± 0.32
Thalamus5.67 ± 0.33
White Matter6.97 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI461788CBCerebellum2.44
3.84
AI461788CTXCerebral cortex1.53
1.44
AI461788HIPHippocampal region3.07
2.76
AI461788HPFHippocampal formation1.94
1.62
AI461788HYHypothalamus0.21
0.36
AI461788LSXLateral septal complex0.22
0.12
AI461788MBMidbrain0.54
0.57
AI461788MYMedulla1.27
1.59
AI461788OLFOlfactory bulb1.75
2.58
AI461788PPons0.45
0.68
AI461788PALPallidum0.16
0.17
AI461788RHPRetrohippocampal region0.78
0.57
AI461788sAMYStriatum-like amygdalar nuclei0.36
0.75
AI461788STRStriatum0.26
0.24
AI461788STRdStriatum dorsal region0.16
0.12
AI461788STRvStriatum ventral region0.59
0.51
AI461788THThalamus0.59
0.44
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018