AutismKB 2.0

Annotation Detail for GNPDA2


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Basic Information Top
Gene Symbol:GNPDA2 ( GNP2,SB52 )
Gene Full Name: glucosamine-6-phosphate deaminase 2
Band: 4p12
Quick LinksEntrez ID:132789; OMIM: 613222; Uniprot ID:GNPI2_HUMAN; ENSEMBL ID: ENSG00000163281; HGNC ID: 21526
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus16 / 56401228
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult56 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor3 / 26384511
glioma11 / 106883102
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia4 / 9725041
normal109 / 336030732
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood2 / 12347816
bone3 / 7165541
bone marrow1 / 4880120
brain64 / 110098958
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine2 / 2344728
kidney9 / 21177742
larynx0 / 241450 
liver6 / 20774328
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle7 / 10771564
nerve1 / 1576863
ovary4 / 10205139
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta2 / 2808257
prostate3 / 18934515
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach3 / 9661931
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11093_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.8 ± 0.33
Basal Forebrain5.67 ± 0.19
Basal Part of Pons5.86 ± 0.32
Cerebellar Cortex6.17 ± 0.21
Cerebellar Nuclei5.89 ± 0.39
Claustrum5.64 ± 0.39
Epithalamus5.57 ± 0.44
Frontal Lobe5.82 ± 0.38
Globus Pallidus5.1 ± 0.35
Hypothalamus5.78 ± 0.16
Insula5.82 ± 0.23
Limbic Lobe5.85 ± 0.46
Mesencephalon5.61 ± 0.51
Myelencephalon5.67 ± 0.48
Occipital Lobe5.75 ± 0.43
Parietal Lobe5.81 ± 0.37
Pontine Tegmentum5.83 ± 0.37
Striatum5.26 ± 0.36
Subthalamus5.52 ± 0.83
Temporal Lobe5.81 ± 0.36
Thalamus5.69 ± 0.34
White Matter5.09 ± 0.09
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gnpda2CBCerebellum3.71
5.39
Gnpda2CTXCerebral cortex13.13
10.29
Gnpda2HIPHippocampal region4.03
3.63
Gnpda2HPFHippocampal formation3.12
2.84
Gnpda2HYHypothalamus1.86
1.87
Gnpda2LSXLateral septal complex2.6
1.7
Gnpda2MBMidbrain2.34
3.13
Gnpda2MYMedulla1.47
2.02
Gnpda2OLFOlfactory bulb4.79
4.47
Gnpda2PPons1.33
2.04
Gnpda2PALPallidum0.82
0.72
Gnpda2RHPRetrohippocampal region1.63
1.67
Gnpda2sAMYStriatum-like amygdalar nuclei2.36
2.11
Gnpda2STRStriatum0.94
0.74
Gnpda2STRdStriatum dorsal region0.26
0.22
Gnpda2STRvStriatum ventral region1.64
1.13
Gnpda2THThalamus1.08
0.91
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00008888 17 34 50 YFTLGLPTGSTPLGCYK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018