AutismKB 2.0

Annotation Detail for ADM


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Basic Information Top
Gene Symbol:ADM ( AM )
Gene Full Name: adrenomedullin
Band: 11p15.4
Quick LinksEntrez ID:133; OMIM: 103275; Uniprot ID:ADML_HUMAN; ENSEMBL ID: ENSG00000148926; HGNC ID: 259
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst11 / 62319176
fetus21 / 56401237
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult203 / 1939121104
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor2 / 3436658
chondrosarcoma16 / 82823193
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor8 / 26384530
glioma17 / 106883159
head and neck tumor9 / 13630266
kidney tumor12 / 68959174
leukemia1 / 9584210
liver tumor12 / 96359124
lung tumor1 / 1031279
lymphoma2 / 7175527
non-neoplasia2 / 9725020
normal317 / 336030794
ovarian tumor1 / 7668213
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood5 / 12347840
bone3 / 7165541
bone marrow0 / 488010 
brain46 / 110098941
cervix2 / 4817141
connective tissue15 / 149255100
ear1 / 1621261
embryonic tissue29 / 215722134
esophagus2 / 2020998
eye22 / 211054104
heart3 / 8962633
intestine9 / 23447238
kidney22 / 211777103
larynx2 / 2414582
liver15 / 20774372
lung22 / 33697465
lymph0 / 442700 
lymph node0 / 916100 
mammary gland8 / 15327152
mouth4 / 6705259
muscle5 / 10771546
nerve4 / 15768253
ovary8 / 10205178
pancreas13 / 21481260
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta123 / 280825437
prostate1 / 1893455
salivary gland2 / 2015599
skin23 / 210574109
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus21 / 23287890
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202912_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.45
Adipocyte859
AdrenalCortex34.3
Adrenalgland35.05
Amygdala13.3
Appendix386.25
AtrioventricularNode24.35
BDCA4+_DentriticCells21.65
Bonemarrow45.65
BronchialEpithelialCells233.35
CD105+_Endothelial12.9
CD14+_Monocytes22.3
CD19+_BCells(neg._sel.)13.4
CD33+_Myeloid71.5
CD34+15.75
CD4+_Tcells13.1
CD56+_NKCells15
CD71+_EarlyErythroid13.6
CD8+_Tcells11.2
CardiacMyocytes108.7
Caudatenucleus12
Cerebellum10.15
CerebellumPeduncles14.8
CiliaryGanglion245.95
CingulateCortex29.1
Colorectaladenocarcinoma25.4
DorsalRootGanglion14.65
FetalThyroid14.15
Fetalbrain73.75
Fetalliver9
Fetallung220.2
GlobusPallidus11.15
Heart20.55
Hypothalamus47.35
Kidney73.75
Leukemia_chronicMyelogenousK-56211.55
Leukemia_promyelocytic-HL-6011.15
Leukemialymphoblastic(MOLT-4)9.8
Liver16.9
Lung938.95
Lymphnode33.6
Lymphoma_burkitts(Daudi)16.05
Lymphoma_burkitts(Raji)17.75
MedullaOblongata11.45
OccipitalLobe8.9
OlfactoryBulb141.55
Ovary23.6
Pancreas279.9
PancreaticIslet463.2
ParietalLobe13.3
Pituitary47.35
Placenta3424.05
Pons31.7
PrefrontalCortex17.7
Prostate29.3
Salivarygland23.15
SkeletalMuscle53.9
Skin477.55
SmoothMuscle451.35
Spinalcord103.25
SubthalamicNucleus21.05
SuperiorCervicalGanglion97.85
TemporalLobe32
Testis10.9
TestisGermCell13.55
TestisIntersitial10.7
TestisLeydigCell12.5
TestisSeminiferousTubule11.9
Thalamus37
Thymus22.45
Thyroid59.3
Tongue244.8
Tonsil17.1
Trachea130.35
TrigeminalGanglion195.55
Uterus24.35
UterusCorpus71.85
WholeBlood331.5
Wholebrain11.1
colon70.55
pineal_day13.8
pineal_night12.44
retina667.425
small_intestine74.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P127948
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.09 ± 0.8
Basal Forebrain7.09 ± 0.37
Basal Part of Pons6.36 ± 0.57
Cerebellar Cortex6.53 ± 0.34
Cerebellar Nuclei8.41 ± 0.55
Claustrum6.39 ± 0.64
Epithalamus8.13 ± 0.67
Frontal Lobe6.98 ± 0.66
Globus Pallidus10.39 ± 0.93
Hypothalamus7.5 ± 0.81
Insula6.87 ± 0.48
Limbic Lobe6.6 ± 0.73
Mesencephalon7.84 ± 0.75
Myelencephalon7.33 ± 0.81
Occipital Lobe8.13 ± 0.78
Parietal Lobe7.31 ± 0.74
Pontine Tegmentum7.77 ± 0.57
Striatum8.85 ± 1.08
Subthalamus8.17 ± 0.46
Temporal Lobe7.07 ± 0.57
Thalamus8.5 ± 0.7
White Matter7.41 ± 1.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AdmCBCerebellum0.68
1.5
AdmCTXCerebral cortex1.85
1.65
AdmHIPHippocampal region0.74
0.78
AdmHPFHippocampal formation1
1.03
AdmHYHypothalamus2
3.83
AdmLSXLateral septal complex0.19
0.18
AdmMBMidbrain1.22
1.72
AdmMYMedulla2.27
4.02
AdmOLFOlfactory bulb4.62
4.43
AdmPPons3.62
6.2
AdmPALPallidum0.4
0.94
AdmRHPRetrohippocampal region1.48
1.4
AdmsAMYStriatum-like amygdalar nuclei0.71
1.21
AdmSTRStriatum0.49
0.62
AdmSTRdStriatum dorsal region0.34
0.25
AdmSTRvStriatum ventral region0.92
1.45
AdmTHThalamus2.38
2.2
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ADML_HUMAN_99 8 99 106 MNNFQGLR PRIDE
PAp00136307 14 61 74 AGPAQTLIRPQDMK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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