AutismKB 2.0

Annotation Detail for PACRGL


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Basic Information Top
Gene Symbol:PACRGL ( C4orf28,MGC29898 )
Gene Full Name: PARK2 co-regulated-like
Band: 4p15.31
Quick LinksEntrez ID:133015; OMIM: NA; Uniprot ID:PACRL_HUMAN; ENSEMBL ID: ENSG00000163138; HGNC ID: 28442
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus19 / 56401233
neonate3 / 3109796
infant1 / 2362042
juvenile0 / 555560 
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor1 / 1193698
germ cell tumor6 / 26384522
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal101 / 336030730
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood5 / 12347840
bone0 / 716550 
bone marrow1 / 4880120
brain30 / 110098927
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary1 / 1020519
pancreas10 / 21481246
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen4 / 5395274
stomach2 / 9661920
testis25 / 33044275
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7489_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.48 ± 0.53
Basal Forebrain6.55 ± 0.21
Basal Part of Pons6.57 ± 0.44
Cerebellar Cortex6.07 ± 0.24
Cerebellar Nuclei5.99 ± 0.47
Claustrum6.18 ± 0.51
Epithalamus6.63 ± 0.63
Frontal Lobe6.56 ± 0.36
Globus Pallidus6.23 ± 0.5
Hypothalamus6.36 ± 0.38
Insula6.76 ± 0.26
Limbic Lobe6.78 ± 0.43
Mesencephalon6.43 ± 0.29
Myelencephalon6.42 ± 0.45
Occipital Lobe6.31 ± 0.43
Parietal Lobe6.49 ± 0.36
Pontine Tegmentum6.49 ± 0.47
Striatum6.77 ± 0.33
Subthalamus6.1 ± 0.61
Temporal Lobe6.6 ± 0.38
Thalamus6.26 ± 0.36
White Matter6.65 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
4933428G09RikCBCerebellum4.16
7.2
4933428G09RikCTXCerebral cortex1.81
1.68
4933428G09RikHIPHippocampal region4.06
3.72
4933428G09RikHPFHippocampal formation3.92
3.7
4933428G09RikHYHypothalamus5.4
4.63
4933428G09RikLSXLateral septal complex3.34
3.65
4933428G09RikMBMidbrain1.03
2.11
4933428G09RikMYMedulla1.87
2.9
4933428G09RikOLFOlfactory bulb15.22
14.52
4933428G09RikPPons5.06
7.51
4933428G09RikPALPallidum3.42
2.86
4933428G09RikRHPRetrohippocampal region3.55
3.89
4933428G09RiksAMYStriatum-like amygdalar nuclei4.28
3.48
4933428G09RikSTRStriatum3.21
2.65
4933428G09RikSTRdStriatum dorsal region1.99
1.69
4933428G09RikSTRvStriatum ventral region7.77
5.58
4933428G09RikTHThalamus1.52
1.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018