AutismKB 2.0

Annotation Detail for EGFLAM


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Basic Information Top
Gene Symbol:EGFLAM ( AGRINL,AGRNL,FLJ39155 )
Gene Full Name: EGF-like, fibronectin type III and laminin G domains
Band: 5p13.2-p13.1
Quick LinksEntrez ID:133584; OMIM: NA; Uniprot ID:EGFLA_HUMAN; ENSEMBL ID: ENSG00000164318; HGNC ID: 26810
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal117 / 336030734
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain13 / 110098911
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye17 / 21105480
heart1 / 8962611
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver1 / 2077434
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland2 / 15327113
mouth1 / 6705214
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta35 / 280825124
prostate16 / 18934584
salivary gland0 / 201550 
skin1 / 2105744
spleen2 / 5395237
stomach0 / 966190 
testis14 / 33044242
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus10 / 23287842
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6228_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.17 ± 1.11
Basal Forebrain2.7 ± 0.33
Basal Part of Pons3 ± 0.54
Cerebellar Cortex2.45 ± 0.77
Cerebellar Nuclei2.78 ± 0.9
Claustrum3.44 ± 0.88
Epithalamus2.37 ± 0.98
Frontal Lobe2.61 ± 0.86
Globus Pallidus3.16 ± 0.92
Hypothalamus2.56 ± 1.14
Insula2.67 ± 0.88
Limbic Lobe2.79 ± 0.8
Mesencephalon2.84 ± 0.78
Myelencephalon2.9 ± 0.76
Occipital Lobe2.72 ± 0.88
Parietal Lobe2.95 ± 0.78
Pontine Tegmentum2.73 ± 0.96
Striatum3.12 ± 0.82
Subthalamus3.04 ± 0.3
Temporal Lobe2.74 ± 0.84
Thalamus2.99 ± 0.69
White Matter3.49 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AU040377CBCerebellum3.34
4.26
AU040377CTXCerebral cortex1.68
1.58
AU040377HIPHippocampal region1.74
2.48
AU040377HPFHippocampal formation1.9
2.22
AU040377HYHypothalamus1.7
1.72
AU040377LSXLateral septal complex3.14
4.4
AU040377MBMidbrain3.5
3.8
AU040377MYMedulla3.85
4.36
AU040377OLFOlfactory bulb3.84
3.66
AU040377PPons4.49
5.68
AU040377PALPallidum0.82
1
AU040377RHPRetrohippocampal region2.15
1.71
AU040377sAMYStriatum-like amygdalar nuclei0.8
0.83
AU040377STRStriatum1.34
1.21
AU040377STRdStriatum dorsal region1.39
1.08
AU040377STRvStriatum ventral region0.87
0.78
AU040377THThalamus2.26
2.22
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01428124 9 196 204 IQMDSMVIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018