AutismKB 2.0

Annotation Detail for POC5


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Basic Information Top
Gene Symbol:POC5 ( C5orf37,FLJ35779,MGC120442,MGC120443,MGC120444 )
Gene Full Name: POC5 centriolar protein homolog (Chlamydomonas)
Band: 5q13.3
Quick LinksEntrez ID:134359; OMIM: NA; Uniprot ID:POC5_HUMAN; ENSEMBL ID: ENSG00000152359; HGNC ID: 26658
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus18 / 56401231
neonate2 / 3109764
infant1 / 2362042
juvenile2 / 5555635
adult127 / 193912165
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor3 / 17290173
gastrointestinal tumor2 / 11936916
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal93 / 336030727
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer93 / 102680905
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone2 / 7165527
bone marrow4 / 4880181
brain20 / 110098918
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus3 / 20209148
eye5 / 21105423
heart0 / 896260 
intestine4 / 23447217
kidney6 / 21177728
larynx0 / 241450 
liver5 / 20774324
lung3 / 3369748
lymph0 / 442700 
lymph node5 / 9161054
mammary gland4 / 15327126
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid2 / 2053997
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate93 / 189345491
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis21 / 33044263
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P413803
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.34 ± 0.54
Basal Forebrain4.29 ± 0.4
Basal Part of Pons4.49 ± 0.39
Cerebellar Cortex4.67 ± 0.3
Cerebellar Nuclei4.58 ± 0.32
Claustrum4 ± 0.57
Epithalamus4.24 ± 0.4
Frontal Lobe4.34 ± 0.45
Globus Pallidus4.62 ± 0.28
Hypothalamus4.64 ± 0.47
Insula4.11 ± 0.47
Limbic Lobe4.27 ± 0.58
Mesencephalon4.38 ± 0.51
Myelencephalon4.32 ± 0.52
Occipital Lobe4.29 ± 0.47
Parietal Lobe4.23 ± 0.49
Pontine Tegmentum4.39 ± 0.44
Striatum4.58 ± 0.48
Subthalamus4.4 ± 0.19
Temporal Lobe4.28 ± 0.43
Thalamus4.23 ± 0.55
White Matter5.63 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1200014M14RikCBCerebellum12.89
16.27
1200014M14RikCTXCerebral cortex14.1
11.52
1200014M14RikHIPHippocampal region23.25
29.88
1200014M14RikHPFHippocampal formation22.57
25.48
1200014M14RikHYHypothalamus4.2
3.6
1200014M14RikLSXLateral septal complex0.18
0.23
1200014M14RikMBMidbrain3.91
4.64
1200014M14RikMYMedulla24.15
28.97
1200014M14RikOLFOlfactory bulb35.76
31.05
1200014M14RikPPons15.02
18.07
1200014M14RikPALPallidum5.7
6.15
1200014M14RikRHPRetrohippocampal region21.59
18.29
1200014M14RiksAMYStriatum-like amygdalar nuclei19.64
14.42
1200014M14RikSTRStriatum10.54
8.55
1200014M14RikSTRdStriatum dorsal region9.3
7.85
1200014M14RikSTRvStriatum ventral region17.77
13.4
1200014M14RikTHThalamus5.02
4.64
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018