AutismKB 2.0

Annotation Detail for NUDCD2


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Basic Information Top
Gene Symbol:NUDCD2 ( DKFZp686E10109 )
Gene Full Name: NudC domain containing 2
Band: 5q34
Quick LinksEntrez ID:134492; OMIM: NA; Uniprot ID:NUDC2_HUMAN; ENSEMBL ID: ENSG00000170584; HGNC ID: 30535
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult44 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma4 / 17475228
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal74 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder4 / 29757134
blood0 / 1234780 
bone4 / 7165555
bone marrow1 / 4880120
brain35 / 110098931
cervix0 / 481710 
connective tissue5 / 14925533
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine4 / 23447217
kidney14 / 21177766
larynx2 / 2414582
liver2 / 2077439
lung28 / 33697483
lymph1 / 4427022
lymph node4 / 9161043
mammary gland3 / 15327119
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas2 / 2148129
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta5 / 28082517
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P360245
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.39 ± 0.32
Basal Forebrain8.74 ± 0.14
Basal Part of Pons8.77 ± 0.27
Cerebellar Cortex8.45 ± 0.14
Cerebellar Nuclei9.08 ± 0.35
Claustrum8.34 ± 0.61
Epithalamus8.93 ± 0.41
Frontal Lobe8.86 ± 0.32
Globus Pallidus9.57 ± 0.24
Hypothalamus8.81 ± 0.2
Insula8.77 ± 0.29
Limbic Lobe8.46 ± 0.38
Mesencephalon8.71 ± 0.48
Myelencephalon8.71 ± 0.37
Occipital Lobe8.38 ± 0.36
Parietal Lobe8.78 ± 0.31
Pontine Tegmentum8.8 ± 0.31
Striatum8.8 ± 0.23
Subthalamus9.06 ± 0.31
Temporal Lobe8.66 ± 0.29
Thalamus8.75 ± 0.38
White Matter10.32 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nudcd2CBCerebellum0.45
0.79
Nudcd2CTXCerebral cortex0.35
0.71
Nudcd2HIPHippocampal region0.29
0.28
Nudcd2HPFHippocampal formation0.25
0.25
Nudcd2HYHypothalamus0.79
1.35
Nudcd2LSXLateral septal complex0.17
0.17
Nudcd2MBMidbrain0.47
1
Nudcd2MYMedulla0.52
0.7
Nudcd2OLFOlfactory bulb1.24
2.62
Nudcd2PPons0.97
1.44
Nudcd2PALPallidum0.18
0.59
Nudcd2RHPRetrohippocampal region0.14
0.21
Nudcd2sAMYStriatum-like amygdalar nuclei0.22
1.17
Nudcd2STRStriatum0.23
0.32
Nudcd2STRdStriatum dorsal region0.14
0.11
Nudcd2STRvStriatum ventral region0.6
0.52
Nudcd2THThalamus0.11
0.23
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NUDC2_HUMAN_2 7 2 8 SAPFEER PRIDE
NUDC2_HUMAN_39 11 39 49 AQDIQCGLQSR PRIDE
PAp00009306 11 40 50 AQDIQCGLQSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018