AutismKB 2.0

Annotation Detail for C6orf57


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Basic Information Top
Gene Symbol:C6orf57 ( MGC104225 )
Gene Full Name: chromosome 6 open reading frame 57
Band: 6q13
Quick LinksEntrez ID:135154; OMIM: NA; Uniprot ID:CF057_HUMAN; ENSEMBL ID: ENSG00000154079; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal29 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain2 / 11009891
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node1 / 9161010
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_351_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.2 ± 0.3
Basal Forebrain7.8 ± 0.13
Basal Part of Pons8.07 ± 0.22
Cerebellar Cortex7.75 ± 0.28
Cerebellar Nuclei7.62 ± 0.18
Claustrum7.83 ± 0.28
Epithalamus7.53 ± 0.25
Frontal Lobe7.77 ± 0.28
Globus Pallidus7.51 ± 0.23
Hypothalamus7.91 ± 0.35
Insula7.86 ± 0.32
Limbic Lobe7.98 ± 0.26
Mesencephalon7.73 ± 0.34
Myelencephalon7.8 ± 0.3
Occipital Lobe7.89 ± 0.22
Parietal Lobe7.89 ± 0.28
Pontine Tegmentum7.79 ± 0.26
Striatum7.72 ± 0.27
Subthalamus7.83 ± 0.14
Temporal Lobe7.93 ± 0.27
Thalamus7.67 ± 0.27
White Matter7.38 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
1110058L19RikCBCerebellum0.42
0.69
1110058L19RikCTXCerebral cortex0.97
1
1110058L19RikHIPHippocampal region4.41
4.03
1110058L19RikHPFHippocampal formation2.9
2.48
1110058L19RikHYHypothalamus0.03
0.05
1110058L19RikLSXLateral septal complex0.06
0.05
1110058L19RikMBMidbrain0.18
0.31
1110058L19RikMYMedulla0.28
0.61
1110058L19RikOLFOlfactory bulb1.46
1.8
1110058L19RikPPons0.31
0.56
1110058L19RikPALPallidum0.07
0.08
1110058L19RikRHPRetrohippocampal region0.57
0.46
1110058L19RiksAMYStriatum-like amygdalar nuclei0.02
0
1110058L19RikSTRStriatum0.21
0.21
1110058L19RikSTRdStriatum dorsal region0.27
0.29
1110058L19RikSTRvStriatum ventral region0.19
0.13
1110058L19RikTHThalamus0.27
0.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018