AutismKB 2.0

Annotation Detail for CPA2


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Basic Information Top
Gene Symbol:CPA2 ( - )
Gene Full Name: carboxypeptidase A2 (pancreatic)
Band: 7q32.2
Quick LinksEntrez ID:1358; OMIM: 600688; Uniprot ID:CBPA2_HUMAN; ENSEMBL ID: ENSG00000158516; HGNC ID: 2297
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal58 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor15 / 104616143
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver4 / 20774319
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas66 / 214812307
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206212_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte5.2
AdrenalCortex4.35
Adrenalgland3.6
Amygdala5.35
Appendix7.45
AtrioventricularNode4.3
BDCA4+_DentriticCells4.4
Bonemarrow4.4
BronchialEpithelialCells4
CD105+_Endothelial4.1
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid5.15
CD34+5.1
CD4+_Tcells5.2
CD56+_NKCells4.8
CD71+_EarlyErythroid3.8
CD8+_Tcells3.95
CardiacMyocytes5.25
Caudatenucleus3.75
Cerebellum3.45
CerebellumPeduncles5.1
CiliaryGanglion3.55
CingulateCortex4.25
Colorectaladenocarcinoma4.25
DorsalRootGanglion9.85
FetalThyroid4.05
Fetalbrain4.2
Fetalliver7.75
Fetallung3.7
GlobusPallidus3.1
Heart5.6
Hypothalamus4.5
Kidney3.5
Leukemia_chronicMyelogenousK-5623.8
Leukemia_promyelocytic-HL-604.35
Leukemialymphoblastic(MOLT-4)3.85
Liver5.7
Lung4.6
Lymphnode3.7
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)7.4
MedullaOblongata4.55
OccipitalLobe3.75
OlfactoryBulb3.7
Ovary4.9
Pancreas8211.8
PancreaticIslet5344.05
ParietalLobe4.7
Pituitary4.8
Placenta4.2
Pons4.95
PrefrontalCortex6.1
Prostate4.9
Salivarygland4.85
SkeletalMuscle5
Skin6.8
SmoothMuscle4.85
Spinalcord6.2
SubthalamicNucleus3.9
SuperiorCervicalGanglion6.75
TemporalLobe3.85
Testis3.6
TestisGermCell3.45
TestisIntersitial3.75
TestisLeydigCell5.35
TestisSeminiferousTubule4.6
Thalamus4.25
Thymus3.9
Thyroid5.25
Tongue5.45
Tonsil5.6
Trachea5.1
TrigeminalGanglion7.4
Uterus3.9
UterusCorpus5.85
WholeBlood4.5
Wholebrain3.45
colon4.2
pineal_day5.16
pineal_night5.02
retina5.075
small_intestine4.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8766_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.04 ± 1.02
Basal Forebrain1.68 ± 0.26
Basal Part of Pons1.3 ± 0.53
Cerebellar Cortex1.46 ± 0.77
Cerebellar Nuclei1.83 ± 0.77
Claustrum2.53 ± 1.23
Epithalamus1.43 ± 1.04
Frontal Lobe1.48 ± 0.68
Globus Pallidus2.67 ± 0.85
Hypothalamus1.75 ± 0.83
Insula1.43 ± 0.38
Limbic Lobe1.58 ± 0.65
Mesencephalon1.94 ± 0.86
Myelencephalon1.64 ± 0.82
Occipital Lobe1.56 ± 0.64
Parietal Lobe1.65 ± 0.84
Pontine Tegmentum1.58 ± 0.68
Striatum1.82 ± 0.85
Subthalamus1.66 ± 0.64
Temporal Lobe1.43 ± 0.61
Thalamus1.57 ± 0.62
White Matter4.48 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cpa2CBCerebellum8.02
9.39
Cpa2CTXCerebral cortex5.98
5.58
Cpa2HIPHippocampal region3.83
4.51
Cpa2HPFHippocampal formation3.18
3.22
Cpa2HYHypothalamus3.06
2.52
Cpa2LSXLateral septal complex0.09
0
Cpa2MBMidbrain3.82
3.71
Cpa2MYMedulla7.5
8.54
Cpa2OLFOlfactory bulb13.12
10.15
Cpa2PPons5.67
6.69
Cpa2PALPallidum6.56
5.69
Cpa2RHPRetrohippocampal region2.18
1.62
Cpa2sAMYStriatum-like amygdalar nuclei4.64
3.31
Cpa2STRStriatum6.59
4.82
Cpa2STRdStriatum dorsal region5.11
3.64
Cpa2STRvStriatum ventral region14.98
10.73
Cpa2THThalamus7.76
6.29
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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