AutismKB 2.0

Annotation Detail for TMEM139


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Basic Information Top
Gene Symbol:TMEM139 ( FLJ90586 )
Gene Full Name: transmembrane protein 139
Band: 7q34
Quick LinksEntrez ID:135932; OMIM: NA; Uniprot ID:TM139_HUMAN; ENSEMBL ID: ENSG00000178826; HGNC ID: 22058
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult49 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal75 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain9 / 11009898
cervix2 / 4817141
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine10 / 23447242
kidney20 / 21177794
larynx0 / 241450 
liver3 / 20774314
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta22 / 28082578
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis4 / 33044212
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P42909
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.11 ± 1.22
Basal Forebrain1.95 ± 0.35
Basal Part of Pons2.28 ± 0.93
Cerebellar Cortex1.72 ± 0.76
Cerebellar Nuclei3.06 ± 1.04
Claustrum2.37 ± 0.67
Epithalamus1.7 ± 0.54
Frontal Lobe1.94 ± 1
Globus Pallidus4.1 ± 0.5
Hypothalamus2.29 ± 1.87
Insula1.37 ± 0.51
Limbic Lobe1.75 ± 0.78
Mesencephalon2.15 ± 1
Myelencephalon1.97 ± 0.94
Occipital Lobe1.88 ± 0.86
Parietal Lobe1.97 ± 0.94
Pontine Tegmentum2.01 ± 0.76
Striatum1.89 ± 0.68
Subthalamus2.2 ± 0.19
Temporal Lobe1.71 ± 0.81
Thalamus1.97 ± 0.74
White Matter5.17 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tmem139CBCerebellum4.89
5.32
Tmem139CTXCerebral cortex2.69
2.77
Tmem139HIPHippocampal region2.45
2.5
Tmem139HPFHippocampal formation2.01
1.89
Tmem139HYHypothalamus1.11
2.75
Tmem139LSXLateral septal complex0.03
0
Tmem139MBMidbrain0.46
0.63
Tmem139MYMedulla2.39
2.81
Tmem139OLFOlfactory bulb6.58
4.72
Tmem139PPons1.19
1.47
Tmem139PALPallidum0.3
0.24
Tmem139RHPRetrohippocampal region1.17
0.91
Tmem139sAMYStriatum-like amygdalar nuclei1.53
1.25
Tmem139STRStriatum0.92
0.66
Tmem139STRdStriatum dorsal region0.87
0.65
Tmem139STRvStriatum ventral region1.35
0.81
Tmem139THThalamus2.92
3.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018