AutismKB 2.0

Annotation Detail for CPD


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Basic Information Top
Gene Symbol:CPD ( GP180 )
Gene Full Name: carboxypeptidase D
Band: 17q11.2
Quick LinksEntrez ID:1362; OMIM: 603102; Uniprot ID:CBPD_HUMAN; ENSEMBL ID: ENSG00000108582; HGNC ID: 2301
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst5 / 6231980
fetus29 / 56401251
neonate5 / 31097160
infant0 / 236200 
juvenile9 / 55556161
adult168 / 193912186
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma3 / 17475171
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma11 / 82823132
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor11 / 11936992
germ cell tumor26 / 26384598
glioma8 / 10688374
head and neck tumor18 / 136302132
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor10 / 96359103
lung tumor4 / 10312738
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal259 / 336030777
ovarian tumor9 / 76682117
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland5 / 33197150
ascites3 / 4001574
bladder2 / 2975767
blood6 / 12347848
bone3 / 7165541
bone marrow6 / 48801122
brain68 / 110098961
cervix2 / 4817141
connective tissue13 / 14925587
ear2 / 16212123
embryonic tissue12 / 21572255
esophagus2 / 2020998
eye13 / 21105461
heart4 / 8962644
intestine15 / 23447263
kidney21 / 21177799
larynx3 / 24145124
liver17 / 20774381
lung29 / 33697486
lymph0 / 442700 
lymph node5 / 9161054
mammary gland13 / 15327184
mouth9 / 67052134
muscle10 / 10771592
nerve2 / 15768126
ovary10 / 10205197
pancreas27 / 214812125
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta29 / 280825103
prostate10 / 18934552
salivary gland2 / 2015599
skin15 / 21057471
spleen1 / 5395218
stomach10 / 96619103
testis60 / 330442181
thymus2 / 8113124
thyroid7 / 47473147
tonsil0 / 169990 
trachea25 / 52413476
umbilical cord2 / 13680146
uterus15 / 23287864
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201942_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.25
Adipocyte7
AdrenalCortex6.7
Adrenalgland5.45
Amygdala6
Appendix6.75
AtrioventricularNode5.75
BDCA4+_DentriticCells7.75
Bonemarrow6.4
BronchialEpithelialCells41.85
CD105+_Endothelial5.95
CD14+_Monocytes9.15
CD19+_BCells(neg._sel.)6.25
CD33+_Myeloid73
CD34+7.4
CD4+_Tcells7
CD56+_NKCells13.5
CD71+_EarlyErythroid5.9
CD8+_Tcells8.2
CardiacMyocytes21.1
Caudatenucleus5.65
Cerebellum5.15
CerebellumPeduncles7.4
CiliaryGanglion4.8
CingulateCortex6.6
Colorectaladenocarcinoma6.1
DorsalRootGanglion5.6
FetalThyroid6.2
Fetalbrain6.05
Fetalliver5.75
Fetallung5.3
GlobusPallidus4.75
Heart8.35
Hypothalamus6.25
Kidney5.3
Leukemia_chronicMyelogenousK-5625.85
Leukemia_promyelocytic-HL-605.55
Leukemialymphoblastic(MOLT-4)4.9
Liver9.5
Lung7.05
Lymphnode5.5
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)9
MedullaOblongata5.95
OccipitalLobe5.5
OlfactoryBulb5.8
Ovary4.4
Pancreas5.35
PancreaticIslet34
ParietalLobe6.9
Pituitary7.35
Placenta12.65
Pons6.1
PrefrontalCortex7.6
Prostate7.2
Salivarygland6.1
SkeletalMuscle8.25
Skin5.3
SmoothMuscle40.25
Spinalcord6.7
SubthalamicNucleus6
SuperiorCervicalGanglion9.2
TemporalLobe5.9
Testis31.55
TestisGermCell147.2
TestisIntersitial326.6
TestisLeydigCell120.4
TestisSeminiferousTubule86.4
Thalamus6.45
Thymus4.75
Thyroid7.6
Tongue6.45
Tonsil6.25
Trachea9.6
TrigeminalGanglion7.65
Uterus5.15
UterusCorpus5.75
WholeBlood40.3
Wholebrain5.2
colon6.5
pineal_day8.88
pineal_night17.5
retina7.55
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P207837
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.58 ± 0.3
Basal Forebrain7.3 ± 0.27
Basal Part of Pons7.35 ± 0.28
Cerebellar Cortex7.24 ± 0.31
Cerebellar Nuclei7.96 ± 0.35
Claustrum7.86 ± 0.71
Epithalamus7.76 ± 0.22
Frontal Lobe7.55 ± 0.43
Globus Pallidus7.93 ± 0.16
Hypothalamus7.28 ± 0.42
Insula7.39 ± 0.27
Limbic Lobe7.79 ± 0.43
Mesencephalon7.59 ± 0.57
Myelencephalon7.63 ± 0.41
Occipital Lobe7.77 ± 0.35
Parietal Lobe7.57 ± 0.43
Pontine Tegmentum7.73 ± 0.34
Striatum7.67 ± 0.33
Subthalamus7.97 ± 0.34
Temporal Lobe7.54 ± 0.34
Thalamus7.68 ± 0.28
White Matter9.07 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CpdCBCerebellum17.64
18.12
CpdCTXCerebral cortex47.35
38.49
CpdHIPHippocampal region43.23
77.71
CpdHPFHippocampal formation44.34
62.08
CpdHYHypothalamus10.62
7.8
CpdLSXLateral septal complex17.19
14.06
CpdMBMidbrain20.75
16.91
CpdMYMedulla36.82
34.07
CpdOLFOlfactory bulb60.52
60.56
CpdPPons37.3
32.59
CpdPALPallidum10.32
8.99
CpdRHPRetrohippocampal region46.33
41.76
CpdsAMYStriatum-like amygdalar nuclei16.25
15.2
CpdSTRStriatum15.25
11.83
CpdSTRdStriatum dorsal region15.68
12.37
CpdSTRvStriatum ventral region12.22
7.71
CpdTHThalamus20.92
18.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CBPD_HUMAN_1018 10 1018 1027 NPAVTQLVDR PRIDE
CBPD_HUMAN_1193 9 1193 1201 LPSLWADNK PRIDE
CBPD_HUMAN_1293 6 1293 1298 IFGLPR PRIDE
CBPD_HUMAN_134 13 134 146 LVGNMHGDETVSR PRIDE
CBPD_HUMAN_155 7 155 161 ELAAGYR PRIDE
CBPD_HUMAN_170 20 170 189 LLNTTDVYLLPSLNPDGFER PRIDE
CBPD_HUMAN_294 10 294 303 AYASNHPIMK PRIDE
CBPD_HUMAN_356 8 356 363 YPPASQLR PRIDE
CBPD_HUMAN_559 13 559 571 YIGNMHGNEVVGR PRIDE
CBPD_HUMAN_798 10 798 807 GFVLDATDGR PRIDE
CBPD_HUMAN_88 11 88 98 SVEGRPLWVLR PRIDE
CBPD_HUMAN_908 14 908 921 DLSAENGLESLMLR PRIDE
CBPD_HUMAN_967 20 967 986 HIWSLEISNKPNVSEPEEPK PRIDE
PAp00496943 35 99 133 LTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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