AutismKB 2.0

Annotation Detail for CPE


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Basic Information Top
Gene Symbol:CPE ( - )
Gene Full Name: carboxypeptidase E
Band: 4q32.3
Quick LinksEntrez ID:1363; OMIM: 114855; Uniprot ID:CBPE_HUMAN; ENSEMBL ID: ENSG00000109472; HGNC ID: 2303
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body16 / 70761226
blastocyst3 / 6231948
fetus68 / 564012120
neonate3 / 3109796
infant1 / 2362042
juvenile6 / 55556107
adult212 / 1939121109
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma14 / 82823169
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor9 / 26384534
glioma14 / 106883130
head and neck tumor12 / 13630288
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia15 / 97250154
normal612 / 3360307182
ovarian tumor1 / 7668213
pancreatic tumor110 / 1046161051
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone11 / 71655153
bone marrow0 / 488010 
brain312 / 1100989283
cervix1 / 4817120
connective tissue11 / 14925573
ear17 / 162121048
embryonic tissue26 / 215722120
esophagus0 / 202090 
eye35 / 211054165
heart11 / 89626122
intestine0 / 2344720 
kidney15 / 21177770
larynx5 / 24145207
liver7 / 20774333
lung40 / 336974118
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth1 / 6705214
muscle3 / 10771527
nerve3 / 15768190
ovary1 / 1020519
pancreas240 / 2148121117
parathyroid4 / 20539194
pharynx3 / 4132872
pituitary gland33 / 165851989
placenta4 / 28082514
prostate22 / 189345116
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis27 / 33044281
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord3 / 13680219
uterus4 / 23287817
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201117_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.05
Adipocyte105.15
AdrenalCortex39.7
Adrenalgland106.5
Amygdala3748.3
Appendix80.95
AtrioventricularNode33.45
BDCA4+_DentriticCells5.3
Bonemarrow5.4
BronchialEpithelialCells5
CD105+_Endothelial5.45
CD14+_Monocytes5.45
CD19+_BCells(neg._sel.)5.35
CD33+_Myeloid6.4
CD34+6.3
CD4+_Tcells5.35
CD56+_NKCells5.85
CD71+_EarlyErythroid9.75
CD8+_Tcells4.8
CardiacMyocytes7.5
Caudatenucleus891.9
Cerebellum791.2
CerebellumPeduncles671.1
CiliaryGanglion82.65
CingulateCortex697.75
Colorectaladenocarcinoma5.2
DorsalRootGanglion48.65
FetalThyroid203.75
Fetalbrain620.1
Fetalliver5.65
Fetallung28.95
GlobusPallidus421.15
Heart15.95
Hypothalamus1203.4
Kidney20.35
Leukemia_chronicMyelogenousK-5624.7
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)7.05
Liver7.3
Lung112.25
Lymphnode94.5
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)13.4
MedullaOblongata533.5
OccipitalLobe1170.1
OlfactoryBulb207.85
Ovary34.1
Pancreas32.25
PancreaticIslet1071.55
ParietalLobe526.55
Pituitary1286.6
Placenta5.2
Pons297.25
PrefrontalCortex1804.2
Prostate2045.25
Salivarygland19.7
SkeletalMuscle18.45
Skin22.45
SmoothMuscle7
Spinalcord1090.1
SubthalamicNucleus439.35
SuperiorCervicalGanglion61.9
TemporalLobe401.45
Testis321.9
TestisGermCell245.55
TestisIntersitial80.25
TestisLeydigCell100.2
TestisSeminiferousTubule129.2
Thalamus606.15
Thymus120.2
Thyroid1296.15
Tongue17.65
Tonsil7.8
Trachea80.05
TrigeminalGanglion30.25
Uterus291.95
UterusCorpus11.05
WholeBlood5.6
Wholebrain1180.45
colon149.5
pineal_day1329.8
pineal_night1560.2
retina914.275
small_intestine174.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P34372
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.2 ± 0.34
Basal Forebrain6.18 ± 0.22
Basal Part of Pons5.63 ± 0.52
Cerebellar Cortex5.8 ± 0.39
Cerebellar Nuclei5.45 ± 0.38
Claustrum6.22 ± 0.47
Epithalamus5.91 ± 0.22
Frontal Lobe5.83 ± 0.41
Globus Pallidus6.42 ± 0.29
Hypothalamus6.04 ± 0.25
Insula5.92 ± 0.44
Limbic Lobe6.01 ± 0.53
Mesencephalon5.86 ± 0.47
Myelencephalon5.84 ± 0.48
Occipital Lobe6.02 ± 0.41
Parietal Lobe5.78 ± 0.46
Pontine Tegmentum5.9 ± 0.4
Striatum6.22 ± 0.37
Subthalamus5.73 ± 0.67
Temporal Lobe5.72 ± 0.38
Thalamus5.92 ± 0.37
White Matter4.14 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CpeCBCerebellum100
100
CpeCTXCerebral cortex100
100
CpeHIPHippocampal region100
100
CpeHPFHippocampal formation100
100
CpeHYHypothalamus100
100
CpeLSXLateral septal complex100
100
CpeMBMidbrain100
100
CpeMYMedulla100
100
CpeOLFOlfactory bulb100
100
CpePPons98.92
100
CpePALPallidum100
100
CpeRHPRetrohippocampal region100
100
CpesAMYStriatum-like amygdalar nuclei100
100
CpeSTRStriatum100
100
CpeSTRdStriatum dorsal region100
100
CpeSTRvStriatum ventral region100
100
CpeTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039597 18 284 301 AYSSFNPAMSDPNRPPCR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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