AutismKB 2.0

Annotation Detail for CLDN23


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Basic Information Top
Gene Symbol:CLDN23 ( CLDNL,hCG1646163 )
Gene Full Name: claudin 23
Band: 8p23.1
Quick LinksEntrez ID:137075; OMIM: 609203; Uniprot ID:CLD23_HUMAN; ENSEMBL ID: ; HGNC ID: 17591
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus7 / 56401212
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal42 / 336030712
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine12 / 23447251
kidney2 / 2117779
larynx2 / 2414582
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node10 / 91610109
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate2 / 18934510
salivary gland1 / 2015549
skin3 / 21057414
spleen0 / 539520 
stomach5 / 9661951
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8234_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.18 ± 1.12
Basal Forebrain1.57 ± 0.23
Basal Part of Pons1.35 ± 0.38
Cerebellar Cortex1.75 ± 0.93
Cerebellar Nuclei1.99 ± 0.71
Claustrum2.56 ± 0.98
Epithalamus1.41 ± 1
Frontal Lobe1.55 ± 0.74
Globus Pallidus2.28 ± 0.75
Hypothalamus1.71 ± 0.75
Insula1.65 ± 0.52
Limbic Lobe1.73 ± 0.65
Mesencephalon1.87 ± 0.74
Myelencephalon1.75 ± 0.71
Occipital Lobe1.65 ± 0.63
Parietal Lobe1.83 ± 0.84
Pontine Tegmentum1.77 ± 0.73
Striatum1.79 ± 0.67
Subthalamus1.84 ± 0.68
Temporal Lobe1.69 ± 0.73
Thalamus1.67 ± 0.65
White Matter1.85 ± 0.11
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018